Examples of 'downregulated' in a sentence
Meaning of "downregulated"
downregulated (verb) - refers to the process of decreasing the activity or expression of a gene, protein, or other biological molecule
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- simple past tense and past participle of downregulate
How to use "downregulated" in a sentence
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downregulated
Expression of most of the altered genes was downregulated.
This gene is significantly downregulated in primary brain tumors.
Genes that are almost exclusively expressed in glia are significantly downregulated.
The hormone prolactin is downregulated by dopamine and is upregulated by oestrogen.
It is upregulated by prolactin and androgens and downregulated by estrogen.
It is downregulated in this process.
It plays a role in embryogenesis and is downregulated in adult tissues.
It is downregulated by inflammatory cytoquines, leading to a procoagulant state of the endothelium.
The latter of which were shown to be downregulated below control levels.
Or it will be hooked up in such a way … that it is desensitized or downregulated.
Dicer has been shown to be downregulated due to aging and in many disease states.
This indicates that in this patient the relevant a cell antigens were downregulated or switched off.
Its expression is downregulated in the stationary phase of cell-growth.
They are not normally present in the cells and are downregulated and degraded afterwards.
The following genes downregulated vÃa process d, msbB and optionally htrB.
See also
Analysis of the bones biochemically showed that PTEN was downregulated.
The following gene is downregulated vÃa process d, msbB.
In some embodiments, the pfkB gene is downregulated.
The number of TDFs that were up - or downregulated increased with time after inoculation.
In an embodiment, a ptsH gene encoding HPr is downregulated.
Notch1 expression was downregulated in the adult.
In addition, several other erythroid genes were downregulated.
The two downregulated metabolites, gluconic acid, and maltotriose are related to carbohydrate metabolism.
The results of this analysis indicate that several miRNAs are downregulated during normal megakaryocytic differentiation.
In certain embodiments, the immune response is inhibited or downregulated.
Stem cell-associated genes will be downregulated after differentiation.
In an embodiment, a ackA gene encoding acetate kinase is downregulated.
On the other hand, the downregulated genes were related to metabolic processes and epidermal differentiation.
The RASSF family of tumor suppressors proteins are frequently downregulated in human cancer cells.
Upon differentiation, nestin becomes downregulated and is replaced by tissue-specific intermediate filament proteins.
In another embodiment, a ptsG gene encoding EIICBGlc is downregulated.
The rCTB downregulated the IgG-antibody response in mucous secretion of the co-administered antigen.
Orit willbe hookedup insuch a way… that it is desensitized or downregulated.
Downregulated genes in oxidative phosphorylation pathway . Gene.
In a yet another embodiment, a crr gene encoding EIIAGlc is downregulated.
Downregulated genes in fatty acid metabolism pathway . Gene.
In another preferred instance, expression or function is downregulated as compared to a control.
Many carbohydrate metabolism genes like GAPDH, triosephosphate isomerase and malate dehydrogenase precursor were downregulated.
In some embodiments, the PTS is downregulated by downregulation of the pts operon.
In another embodiment, a fba gene encoding fructose bisphosphate aldolase is downregulated.
These results indicate that Flt4 was downregulated during the differentiation of these cells.
In yet another embodiment, a gltA gene encoding citrate synthase is downregulated.
Have also shown that the conditions for obtaining downregulated expression of HKT1 are quite complex.
As these additional layers form the apical-basal polarity must be downregulated.
IL-8 production was significantly downregulated in the presence of both live and inactivated LGG.
Antidote production may be upregulated in normal cells and / or downregulated in target cells.
The GSEA revealed that cortistatin A downregulated a set of genes that are upregulated upon GSK3-beta inhibition.
Expression is high during the creation of first synaptic contacts, but subsequently downregulated.
For example, expression of the FAS gene may be downregulated to increase PUFA production.
The higher the concentration of threonine or lysine, the more aspartate kinase becomes downregulated.
