Examples of 'endogenous gene' in a sentence
Meaning of "endogenous gene"
endogenous gene - Denotes a gene or genetic material that originates from within an organism or cell, rather than being acquired from an external source
How to use "endogenous gene" in a sentence
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endogenous gene
Such a gene may be an endogenous gene or a transgene.
The endogenous gene promoter can also be used.
Transcription of the endogenous gene can be modulated.
In this example there is no silencing of the endogenous gene.
Expression of an endogenous gene may also be reduced if it contains a mutation.
It is preferred that the selected gene is an endogenous gene.
The endogenous gene preferably thus does not form part of an endogenous operon.
This demonstrates repression of an endogenous gene.
Suppression of endogenous gene expression can for instance be achieved using a ribozyme.
This transgene may contain the endogenous gene.
Regulation of endogenous gene expression is tested using any one of the assays described herein.
In an aspect a gene is an endogenous gene.
DNA constructs for endogenous gene activation and expression modification.
One could also deliver a modulating agent targeting an endogenous gene.
These promoters are used to replace the cognate endogenous gene promoters by homologous recombination.
See also
A therapeutic nucleic acid may also inhibit expression of an endogenous gene.
The HNA can be either an endogenous gene or heterologous.
A microorganism may be modified to modulate the expression level of an endogenous gene.
Preferred assays for ZFP regulation of endogenous gene expression can be performed in vitro.
The constructs further contain one or more exons of the endogenous gene.
The expression of an endogenous gene can also be inhibited by using a DNA encoding a ribozyme.
Such a gene is an endogenous gene.
Targeted genetic alterations can introduce a desired change to a specific location in an endogenous gene.
Plant cells are transformed with a copy of the endogenous gene targeted for repression.
A heterologous gene is overexpressed if its expression is higher than that of a comparable endogenous gene.
Suppression of endogenous gene expression can be carried out using DNA coding for a ribozyme.
The microorganism may express an attenuated level of an endogenous gene encoding a thioesterase.
First, the endogenous gene can be directly mutated.
We have disclosed RNAi polynucleotide delivery resulting in inhibition of endogenous gene expression in hepatocytes.
In this way, an endogenous gene can be turned on or its expression maintained.
By homologous recombination the defective gene replaces the endogenous gene or gene fragment.
An endogenous gene may be present in the nuclear genome, mitochondrial genome etc.
Human erythropoietin and analogous proteins as defined above can be expressed by endogenous gene activation.
Using an appropriate pIR, the endogenous gene of interest is suppressed.
Preferably the first cistron of the polycistronic expression unit will be a strongly expressed endogenous gene.
The combination of knockout of an endogenous gene and rescue by using mutated, e . g.
The FPP synthase polypeptide can be an endogenous polypeptide encoded by an endogenous gene.
In one embodiment in which the endogenous gene is altered, the gene is activated.
The recombinant microorganism comprises a deletion or disruption of an endogenous gene encoding GPD.
That is, both copies of an endogenous gene must be defective for symptoms to appear.
The introduced sequence generally will be substantially identical to the endogenous gene targeted for repression.
Wherein said target endogenous gene is regulated systemically in at least one plant organ ;.
A LCR is not required to open the chromatin structure at an endogenous gene locus.
Such endogenous gene segments include diversity, joining and constant region gene segments.
Genes from a GMO may pass to another organism just like an endogenous gene.
In particular, by directly activating of specific endogenous gene expression with CRISPR-mediated activator.
In an embodiment, it is preferred that the gene is an endogenous gene.
The host cell may not include an endogenous gene encoding an acyl-CoA synthetase.
In an aspect of the present invention, a gene is an endogenous gene.
These include regulation of endogenous gene expression, transposon taming, viral defense and heterochromatin formation.
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