Examples of 'endothelin receptor' in a sentence
Meaning of "endothelin receptor"
This phrase refers to a type of receptor found in the body, specifically the endothelin receptor. Endothelin receptors are proteins that bind with endothelin, a hormone involved in regulating various physiological functions, such as blood vessel constriction, cell growth, and inflammation. These receptors play a role in cardiovascular health, and abnormalities in endothelin receptor function can contribute to certain cardiovascular diseases
How to use "endothelin receptor" in a sentence
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endothelin receptor
Alternative endothelin receptor antagonists may be considered.
Methods for inhibiting binding of an endothelin peptide to an endothelin receptor are provided.
An endothelin receptor is obtained by culturing this transformant.
Cancer treatment with endothelin receptor antagonists.
Endothelin receptor antagonists have recently been proposed as an alternative to these traditional therapies.
There is uncertainty as to whether endothelin receptor antagonists reduce mortality in this population.
Tracleer tablets belong to the class of medicines called endothelin receptor antagonists.
Use of an endothelin receptor antagonist as emergency contraceptive agent.
The emergency contraceptive agents of the present invention are endothelin receptor antagonists.
It is an endothelin receptor antagonist.
Methods and compositions for emergency contraception using endothelin receptor antagonists.
The disclosure below discusses endothelin receptor antagonists in relation to brain metastasis.
Compounds of the invention may be administered in combination with an endothelin receptor antagonist.
Discloses phenyl pyrazoles as endothelin receptor antagonists for treating cardiovascular or renal disease.
The alkali metal salts of the derivatives are useful as endothelin receptor antagonists.
See also
Endothelin receptor blockers have been reported to protect against injury in renal disease progression.
Methods for the identification and isolation of endothelin receptor subtypes are also provided.
Endothelin receptor antagonist can be used to inhibit the vasoconstrictive effects induced by ET.
None of these documents disclose indane or indene derivatives as pharmaceuticals or endothelin receptor antagonists.
Antagonists of the endothelin receptor may thus be useful in preventing restenosis post PTCA.
Endothelin expresses its physiological action by binding to an endothelin receptor on a target cell membrane.
Bosentan is a dual endothelin receptor antagonist used in the treatment of pulmonary artery hypertension PAH.
Methods for the identification end isolation of endothelin receptor subtypes are also provided.
Two endothelin receptor subtypes ETA and ETB are known so far.
To treat a heart and lung disorder called pulmonary arterial hypertension endothelin receptor antagonist.
Endothelin receptor antagonist Bosentan.
The data show that the compounds of the invention bind to the endothelin receptor.
The pharmacokinetics of the newly synthesised endothelin receptor antagonists were assessed in Wistar rats.
An endothelin receptor blocker includes bosentan, etc.
The present invention relates to the treatment of diabetic ketoacidosis using an endothelin receptor antagonist.
Common side effects of endothelin receptor antagonists can include,.
VolibrisTM contains the medicinal ingredient ambrisentan which is a selective endothelin receptor antagonist.
Today, no endothelin receptor antagonist is marketed yet, several are in clinical trials.
The compounds of formula I given above are endothelin receptor inhibitors.
Endothelin receptor antagonists, as a class, have been associated with liver function abnormalities.
The active peptide is a ligand for endothelin receptor type B EDNRB.
As a consequence, endothelin receptor antagonists have been studied extensively as potential therapeutic agents.
As such, it is used as a biochemical tool in the study of endothelin receptor function.
However, the administration of endothelin receptor antagonists is known to result in headaches in man.
A compound according to any one of claims 1 to 4 for use as an endothelin receptor antagonist.
Although a number of endothelin receptor antagonists are known, there is a continuing need for alternative antagonists.
The compound of Claim 1 for use as an endothelin receptor antagonist.
Endothelin receptor antagonism is quantified by calculating dose ratio shifts at the 30mmHg change level.
Hepatic toxicity was not common, and endothelin receptor antagonists were well tolerated in this population.
Endothelin receptor antagonist, another class of drugs used in PAH.
A DNA sequence encoding the human endothelin receptor according to claim 1.
It is a dual endothelin receptor antagonist, see also, Endothelin receptor antagonist.
Therapeutic compositions comprising a specific endothelin receptor antagonist and a PDE5 inhibitor.
An endothelin receptor antagonist (ERA) is a drug that blocks endothelin receptors.
The compounds ( I ) of the present invention having endothelin receptor antagonistic activities are novel.
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Examples of using Receptor
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Receptor is not sensitive to the type of change
Is that why that receptor network existed
This receptor can exist in three conformations
Examples of using Endothelin
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Alternative endothelin receptor antagonists may be considered
Those receptors differ in their affinity to endothelin
Endothelin also stimulates plasma renin activity
