Examples of 'extracellular domains' in a sentence
Meaning of "extracellular domains"
extracellular domains: In biology, these are regions of proteins that exist outside of cells and play crucial roles in cell communication and signaling
How to use "extracellular domains" in a sentence
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extracellular domains
Some fragments will contain only extracellular domains.
Such extracellular domains can be free or conjugated to other molecules.
An alternative possibility is to detect extracellular domains by means of flow cytometry.
The extracellular domains of such receptors are also useful herein.
Consensus glycosylation sites predicted to fall in extracellular domains are indicated by an asterisk.
The extracellular domains are responsible for the recognition of the target cell.
Alternative mRNA splicing produces several forms of the extracellular domains.
This helps define extracellular domains which might be used as inhibitors.
The hematopoietin receptors comprise two conserved amino acid motifs in their extracellular domains.
The small and large extracellular domains are marked with underlines.
This means there are three links between the TMD and the extracellular domains.
Such extracellular domains free or substantially free of transmembrane and cytoplasmic domains are soluble.
The extent of each of the TCR extracellular domains is somewhat variable.
The extracellular domains of these receptors possess binding sites for a diverse range of protein ligands.
This particular combination of extracellular domains is unique to the Tie receptors.
See also
The extracellular domains of these receptors are known in the art Rosenweig et al.
EpCAM is a transmembrane protein containing three extracellular domains and one cytoplasmic domain.
Its extracellular domains are homologous with and structurally similar to an antibody Fab fragment.
All three sequences showed strong similarity to the extracellular domains of TNFR family members.
These proteins have extracellular domains that interact with each other on adjacent cells.
This soluble TM analog therefore has all the extracellular domains of TM.
The interactions between the extracellular domains of cadherins require the presence of calcium ions.
In addition, soluble truncated constructs containing one or more of the extracellular domains were used.
Some of these extracellular domains are full-length.
This receptor family is characterized by the presence of cysteine-rich motifs in the extracellular domains.
The extracellular domains of proteins are about 4 nm above the heads of the lipids.
In one embodiment of the invention, the extracellular domains are engineered using leucine zippers.
Despite this, differences in ligand binding properties have been noted for certain extracellular domains.
Recombinant extracellular domains of CEACAMs were obtained from commercial sources or produced in-house.
Insertion of zcytor17 receptor or heterodimeric subunit extracellular domains into fusion vector constructs.
The receptors ' extracellular domains bind to their respective hormones with high affinity and specificity.
A single cysteine-rich region is also found in the extracellular domains of the eph-like kinases.
These extracellular domains are useful for in vitro ligand-binding assays, both soluble and solid phase.
Reagents that interfere with the interactions of these extracellular domains will impair cell-to-cell communication.
Each of the extracellular domains contains either two or three immunoglobulin ( Ig ) domains.
Also disclosed are antibodies to the extracellular domains of CCR4.
Sequences of the extracellular domains of PRLR from human, monkey and mouse.
The two variants are identical in their N-terminal extracellular domains.
For example, dimers of the extracellular domains may be engineered using leucine zippers.
Two potential N-linked glycosylation sites are present, one in each of the first extracellular domains.
Adhesion is mediated by interaction between extracellular domains of E-cadherin dimers on adjacent cells.
These variants may be more resistant to cleavage by MMP-2 than wildtype FGFR extracellular domains.
Other specific binding partners such as extracellular domains stimulate in vitro activation of such T-cells.
The extracellular domains of FGFRs ( defined below ) bind to one or more FGFs.
The four grids correspond to the four extracellular domains of CCR5.
Although BACE cleaves the extracellular domains of several transmembrane proteins, its physiological function remains unknown.
The present invention also provides antibodies directed against the extracellular domains of the GPR3.
These soluble extracellular domains of AcPI and IL-1Rrp1 can include or exclude their signal peptide.
Different algorithms may predict, and different systems may express, different extracellular domains for a given FGFR.
Additionally, human zB7R1 extracellular domains may be fused with mCD28 intracellular domains in TEa hybridomas.
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