Examples of 'fab fragments' in a sentence
Meaning of "fab fragments"
This phrase refers to fragments or parts of antibodies, specifically the antigen-binding regions. It is commonly used in the field of immunology and biochemistry to describe these specific regions of antibodies that are responsible for binding to antigens
How to use "fab fragments" in a sentence
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fab fragments
Fab fragments are well known in the art.
The antibodies can also be single chain or FAb fragments.
Fab fragments can be obtained by disulfide reduction.
Natural or analogue FAb fragments.
Fab fragments may be produced by papain digestion of antibodies.
Novel antagonist antibodies and their fab fragments against gpvi and uses thereof.
Fab fragments of the monoclonal antibody may be used.
In the present invention Fab fragments are preferred.
Fab fragments were originally observed following papain digestion of an antibody.
Expression and purification of soluble Fab fragments.
Fab fragments of human monoclonal antibody were prepared by papain digestion.
Characterisation of the human IgE Fab fragments.
Fab fragments can be prepared by papain digestions of whole antibodies.
This was surprisingly found to be true of Fab fragments.
Fab fragments from immunoglobulin g are usually used in diagnoses and therapys.
See also
Expression and purification of humanized Fab fragments.
Fab fragments are generated by cleavage of IgG with papain instead of pepsin.
Papain digestion can lead to the formation of Fab fragments.
Fab fragments were not used because we were simulating the physiological situation.
Preferred antigen binding portions or fragments of antibodies are Fab fragments.
Fab fragments may be generated by using the enzyme papain to cleave an immunoglobulin.
Papain digestion of antibodies produces two identical Fab fragments.
Fab fragments of the antibody retained the capacity to inhibit platelet aggregation.
The binding affinities of soluble Fab fragments were also tested.
Fab fragments are separated from undigested or partially digested antibody using standard chromatography methods.
Intrinsic affinity can be measured using scFv or Fab fragments.
Fab fragments contain only one binding site and therefore will not clear antigen from solution.
The antibodies may be whole or fragments of antibodies such as Fab fragments.
The use of Fab fragments is generally preferred.
Preparation of antibody phagemid vector for monovalent display of Fab fragments.
All four Fab fragments were highly specific.
The present invention relates to the use of immunoglobulin Fab fragments in therapy.
The Fab fragments are recovered in the dead volume.
In one embodiment the first and second Fab fragments are connected vÃa a peptide linker.
The Fab fragments was contained in the first peak.
After four rounds of panning soluble Fab fragments were prepared from eight clones.
The IgG Fab fragments are derived from polyclonal antiserum.
Search for lymphocytic proliferative action of IgG and Fc and Fab fragments of IgG.
Fc and Fab fragments can be generated.
These reagents gain a significant avidity advantage over a single scFv or Fab fragments.
The display of Fab fragments is not part of the invention.
The present invention relates to the production and use of immunoglobulin Fab fragments.
No additional Fab fragments have been clearly identified in the density.
Digestion of an antibody with papain yields individual Fab fragments and the Fc fragment.
Monovalent Fab fragments were prepared and isolated by established methods.
In another preferred embodiment the effective part of the antibody comprises Fab fragments.
Linkage between two Fab fragments is performed between the heavy chains.
The proteolysis of IgG molecule by papain generates two Fab fragments and one Fc fragment.
Such individual Fab fragments can then be tested for antigen specificity.
Fv fragments appear to have lower interaction energy of their two chains than Fab fragments.
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