Examples of 'fc fragments' in a sentence
Meaning of "fc fragments"
fc fragments: This phrase likely refers to the crystallizable fragment of an antibody molecule that can be produced by proteolytic digestion
How to use "fc fragments" in a sentence
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fc fragments
Fc fragments of IgG were isolated and purified as described elsewhere.
They may be replaced by Fc fragments of these immunoglobulins.
Fc fragments may or may not contian extra polypeptide sequence.
Immunomodulating medication based on Fc fragments of human IgG.
Fc fragments may or may not contain extra polypeptide sequence.
Antibodies as disclosed herein may comprise Fc fragments.
Fc fragments are generated entirely from the heavy chain constant region of an immunoglobulin.
Antibodies of the present invention may comprise Fc fragments.
The structure of Fc fragments generally is known in the art.
Other methodologies effective in the purification of Fc fragments also may be employed.
Human Fc fragments will be preferred to make receptorbodies for human administration.
The preparations are free of both Fc fragments and intact IgG.
A variety of other expression systems can be utilized to express recombinant immunoglobulins or Fc fragments.
Fc fragments may result from alternative RNA splicing or from in vivo protease activity.
Said antibodies may comprise Fc fragments.
See also
Human IgG Fc fragments were purchased from Chemicon.
In another case immunoglobulins disclosed herein are isolated Fc regions or Fc fragments.
An Fc preparation comprises Fc fragments of immunoglobulins.
The Fab and Fc fragments may be separated by affinity chromatography on protein A bead columns.
Engineered Fc fragments.
In another embodiment, immunoglobulins disclosed herein are isolated Fc regions or Fc fragments.
Fc fusions and Fc fragments are well-known in the art.
The Fab fragment was separated from intact antibody and Fc fragments by Protein A chromatography.
Fc fragments and undigested immunoglobulins are removed by affinity chromatography on Protein A-Sepharose.
An alternative approach is to use fragments of antibodies, such as Fc fragments of immunoglobulins.
In addition, the present IgG Fc fragments have no risk of inducing immune responses.
A protA sepharose column was used to remove remaining intact antibodies and / or Fc fragments.
Electropherograms of non-reduced Fc fragments are shown before and after enzymatic treatment.
In a specific embodiment, the Fc preparation comprises IgG1 Fc fragments.
In certain embodiments, two Fc fragments may be used, preferably two human Fc fragments.
Fc polypeptides include antibodies, Fc fusions, isolated Fcs, and Fc fragments.
As with isolated Fcs, Fc fragments may or may not contian extra polypeptide sequence.
Antibody fragments include, without limitation, Fab and Fc fragments.
Undigested Ig and Fc fragments were removed by chromatography on protein A-Sepharose.
FIG . 1 shows the results of Western blotting of immunoglobulin Fc fragments expressed in E. coli transformants ;.
Fab fragments were separated from Fc fragments by chromatography on a 1 ml HiTrap Protein G column.
The purified F ( ab ' ) 2 eluted first followed by Fc fragments.
Peak área of enzyme-treated Fc fragments evaluated by CE-SDS.
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