Examples of 'factor xa' in a sentence
Meaning of "factor xa"
Factor Xa is an enzyme that plays a crucial role in the blood coagulation process. It is a component of the coagulation cascade, responsible for initiating the conversion of prothrombin to thrombin, a key step in the formation of blood clots. Factor Xa inhibitors are medications used to prevent the formation of abnormal blood clots and are commonly prescribed for conditions such as deep vein thrombosis and atrial fibrillation
How to use "factor xa" in a sentence
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factor xa
Method for purification of recombinant factor xa derivatives.
Active factor Xa then hydrolyses prothrombin to thrombin.
Compositions and methods for counteracting factor xa inhibition.
Factor Xa excess can be indirectly spectrophotometrically measured.
Unit dose formulation of antidote for factor xa inhibitors for use in preventing bleeding.
Factor Xa has no activity on the commercial substrate.
Unit dose formulation of antidotes for factor xa inhibitors and methods of using the same.
Peptide substrates for the identification of factor Xa.
Methods of making the factor Xa inhibitor are described.
Such proteases include thrombin and factor Xa.
Factor Xa is another serine protease in the coagulation pathway.
Direct thrombin inhibitors and factor Xa inhibitors.
Factor Xa is believed to be the major physiological activator of fVII.
It is thus desirable to discover new factor Xa inhibitors.
Factor Xa is the penultimate enzyme in the coagulation cascade.
See also
Several specific inhibitors of factor Xa have been reported.
Exemplary factor Xa inhibitors include apixaban and rivaroxaban.
Fondaparinux is a synthetic pentasaccharide factor Xa inhibitor.
Factor Xa inhibitors are given to prevent clots in your blood vessels.
The complex predominantly inactivates factor Xa on phospholipid surfaces.
The same applies to the selective inhibitor of factor Xa.
A sample of solution was tested in a factor Xa amidolytic assay as follows.
Compounds of the invention were found to be potent inhibitors of factor Xa.
The appearance and disappearance of factor Xa is governed by thrombin.
A modified aPTT which is dependent on heparin by adding factor Xa.
It is a selective factor Xa inhibitor and thus an inhibitor of thrombin generation.
These compounds are stated to be factor Xa inhibitors.
The amount of factor Xa was calculated by comparison to known factor Xa concentrations.
Inhibitors which covalently bond to the factor Xa are preferred.
The factor Xa is located upstream from thrombin in the coagulation cascade.
The formation of thrombin from prothrombin is catalyzed by factor Xa.
Other compounds having a factor Xa inhibitory activity have been described.
It works as a synthetic selective factor Xa inhibitor.
The factor Xa then converts the prothrombin to thrombin on the medium.
New oxybenzamide derivatives as factor Xa inhibitors.
Both thrombin and factor Xa are validated targets for anticoagulant therapies.
Jackson et al do not teach inhibition of factor Xa.
Studies compared DTIs or factor Xa inhibitors with conventional treatment.
Heparin increases the affinity of antithrombin to thrombin as well as factor Xa.
The catalytic center of factor Xa is located on the heavy chain.
Fondaparinux is a synthetic selective pentasaccharide that indirectly inhibits factor Xa.
Evidence exists for the role of factor Xa inhibitors as anticoagulants.
Rivaroxaban is a selective inhibitor of factor Xa.
This is a highly selective inhibitor of factor Xa in the blood coagulation pathways.
Fondaparinux binds antithrombin and accelerates its inhibition of factor Xa.
Drugs directed against thrombin or the factor Xa are currently available.
An alternative approach for inhibiting thrombin function is to inhibit factor Xa.
The supernatant contained all of the factor Xa inhibitory activity.
Factor Xa has also been used as a trigger in a system utilizing purified components.
No mention is made of using the above compounds as factor Xa inhibitors.
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