Examples of 'fcr binding' in a sentence
Meaning of "fcr binding"
fcr binding - FCR binding is a term used in biochemistry to describe the ability of a transcription factor to bind to a specific DNA sequence and regulate gene expression
How to use "fcr binding" in a sentence
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fcr binding
Such antibody shows reduced FcR binding as indicated above.
FcR binding activity of mAb.
These are thus also included in the term FcR binding peptides.
The results indicate that loss of FcR binding improved the pharmacokinetic behavior somewhat.
An FcR binding peptide also covers cross-linked FcR binding peptide derivatives.
Detecting the amount of FcR binding peptide bound to the Fc receptor.
The CH2 domain is known to mediate complement and FcR binding.
In one embodiment of the present invention, the FcR binding peptide is a monoclonal antibody.
Thus, any assay for FcR binding would register all antibodies of these two subclasses.
In one embodiment of the present invention, the FcR binding peptide is an antibody.
In certain embodiments, the FcR binding assay is an Fc neonatal receptor ( FcRn ) binding assay.
In some embodiments, the Fc region retains or has modified FcR binding capability.
In an exemplary embodiment, the FcR binding portion is a complete Fc region.
Replicate mixtures contained 4 mg / ml hIgG to block the FcR binding site.
A method according to embodiment 92, wherein the FcR binding peptide is an IgGl, λ antibody.
See also
Such Fc region variants may display enhanced or diminished FcR binding and / or ADCC activity.
A method according to embodiment 86, wherein the FcR binding peptide is a monoclonal antibody.
A method according to embodiment 106, wherein the FcR binding peptide is IOT4a.
A method according to embodiment 117, wherein the FcR binding peptide is ibritumomab tiuxetan.
A method according to embodiment 139, wherein the FcR binding peptide is alemtuzumab.
A method according to embodiment 130, wherein the FcR binding peptide is adalimumab.
A method according to embodiment 130, wherein the FcR binding peptide is infliximab.
A method according to embodiment 127, wherein the FcR binding peptide is daclizumab.
A method according to embodiment 135, wherein the FcR binding peptide is pertuzumab.
A method according to embodiment 127, wherein the FcR binding peptide is basiliximab.
A method according to embodiment 117, wherein the FcR binding peptide is tositumomab.
A method according to embodiment 141, wherein the FcR binding peptide is bevacizumab.
A method according to embodiment 135, wherein the FcR binding peptide is trastuzumab.
A method according to embodiment 106, wherein the FcR binding peptide is keliximab.
A method according to embodiment 133, wherein the FcR binding peptide is palivizumab.
A method according to embodiment 114, wherein the FcR binding peptide is cetuximab.
A method according to embodiment 106, wherein the FcR binding peptide is zanolimumab.
A method according to embodiment 106, wherein the FcR binding peptide is clenoliximab.
A method according to embodiment 117, wherein the FcR binding peptide is rituximab.
A method according to embodiment 124, wherein the FcR binding peptide is muromonab.
A method according to embodiment 122, wherein the FcR binding peptide is HuMax-TAC.
A method according to embodiment 114, wherein the FcR binding peptide is HuMax-EGFR, zalutumumab.
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An exemplary FcR is a native sequence human FcR