Examples of 'fcy' in a sentence
Meaning of "fcy"
FCY is a noun that can stand for different things depending on the context, such as a financial institution code or abbreviation for a company or organization
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- Abbreviation of full course yellow.
How to use "fcy" in a sentence
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fcy
Introduction fcy the chairman of the session.
Selection of isotype also affects binding to FcY receptors.
The FcY receptor may be a human high affinity FcYRI.
All antibodies were used as full length mouse FcY versions.
Preferably the first and second FcY receptors are each FcY receptor IIIa.
Thus a cluster stradomer is a biomimetic compound capable of binding two or more FcY receptors.
FcY receptors are defined by their specificity for immunoglobulin subtypes.
The binding affinities of antibodies to those human FcY receptors are assayed as follows.
Moreover, FcY receptors are expressed by all immunologically active cells.
The effector cells kill the target cells by signals transduced from the FcY receptors.
In one embodiment, the FcY receptors are low affinity FcY receptors.
There are several methods by which one can produce a MoAb that avoids FcY receptor interactions.
In another embodiment, the FcY receptor is a human high affinity FcYRI.
In a particular embodiment the Fc receptor is an FcY receptor.
As used herein, FcY receptors include FcYRIII and FcYRII receptors.
See also
A FACS titration was performed to assess binding of FcYRIIIA to FcY.
In one embodiment, the FcY receptor is a human high affinity FcYRI.
In one embodiment the activating Fc receptor is an FcY receptor.
In one preferred embodiment, the FcY receptor a human high affinity FcYRI.
In one aspect the Fey receptors are low affinity FcY receptors.
For example, the FcY receptor can be a human high affinity FcYRI.
ADCC is mediated primarily through a set of closely related FcY receptors.
Today, research is directed toward the immunoglobulin FcY fragment in order to improve antibody properties.
This antibody showed minimal binding to Fc proteins bound to the FcY receptor.
Substantial loss of binding to FcY receptors results in substantial loss of T-cell mitogenic activity.
An example of the ITIM class of inhibitory receptors is the FcY receptor FcYRIIB.
Several families of FcY receptors exist, and different effector cells express different Fc receptors.
This enhanced expression increases the cytotoxic activity of FcY RI cells against targets.
FcY ( gamma ) Receptors bind to antibodies of the IgG class.
Both SAP and CRP augment phagocytosis and bind to Fcy receptors on a variety of cells.
Briefly, 96-well plates were coated in sterile conditions with goat anti human IgG FcY.
Membrane-bound immunoglobulins and FcY receptors are present.
In some aspects, the antibody has increased binding to a FcY receptor.
In a further embodiment, the Fc receptor is FcY activating receptor, particularly, the FcYRIIIA receptor.
Assaying the agent for its ability to activate FcY receptors ; and.
Together with CD64, these two Fcy receptors are the main cellular receptors mediating ADCC.
In yet another embodiment of the present invention, the receptor is an FcY receptor.
However, B cells also express FcY RIIb1, a low affinity IgG receptor.
Said pharmaceutical composition is for administering a therapeutically effective amount of a soluble FcY receptor ( FcYR ).
There are five currently recognised human FcY receptors, FcyR ( I ), FcYRIIa, FcYRIIb, FcYRIIIa and neonatal FcRn.
The invention encompasses molecules with altered affinities for the activating and / or inhibitory FcY receptors.
Preferably, the anti-properdin agent does not substantially activate FcY receptors and / or the classical complement pathway.
Interestingly, inhibition of P-L fusión did not occur with entry vía FcY receptors.
Also provided are IgG2 constant regions with reduced FcY receptor-binding activity.
Moreover, protein A has a specific binding affinity for the human FcY fragment.
In the standard protocol, AIN457 is captured by an anti-human FcY antibody Jackson Immunochemicals ; Cat.
Antibodies lacking an Fc region ( e.g., Fab fragments ) lack binding to FcY receptors.
The disclosure also relates to IgG2 constant regions with reduced FcY receptor-binding activity.
In some embodiments, Fc receptor is a member of FcY receptor family.
When two Fc fragment monomers associate, the resulting Fc fragment has FcY receptor binding activity.
