Examples of 'fucosylated' in a sentence
Meaning of "fucosylated"
Fucosylated is a term used in biochemistry to describe the process of adding fucose sugar residues to molecules like proteins or lipids, often studied in the context of cell signaling and diseases
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- simple past tense and past participle of fucosylate
- modified by the addition of fucosyl groups
How to use "fucosylated" in a sentence
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fucosylated
Primary cell wall xyloglucan is fucosylated.
If a protein is fucosylated it typically happens before galactosylation in the glycosylation pathway.
The monoclonal antibody produced in this condition is partially fucosylated.
The fucosylated HSCs described herein may be used in a variety of ways.
Many of these lactosaminoglycans are fucosylated.
A core fucosylated biantennary chain is the only other demonstrated substrate.
This flow cytometry assay detects fucosylated proteins present on cell surface.
Increased fucosylated glycans have also been observed in patients with rheumatoid arthritis.
Such cells can be modified so that the antibody is not substantially fucosylated.
Disclosed is a purified fucosylated oligosaccharide produced by the methods described herein.
There appears to be much less galactose and about half of galactose residues are fucosylated.
Putative roles for fucosylated glycoproteins in leukocyte adhesion and trafficking were discussed.
The filamentous fungal cells of the present invention lack genes to produce fucosylated heterologous proteins.
The bound fraction is enriched in fucosylated recTSH as compared to the unbound fraction.
The thus fucosylated acceptor substrates are involved in a variety of biological and pathological processes.
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This figure shows an increase in the level of fucosylated immunoglobulin with increasing fibrosis.
A large number of fucosylated glycoproteins are secretary proteins or membrane proteins on the cell surface.
IgG from será are also highly fucosylated.
A majority of the glycans are not fucosylated and are mixtures of neutral and sialylated species.
HCV infected patients with varying levels of fibrosis also had elevated levels of fucosylated IgG.
Isolating said fucosylated oligosaccharide from the host cell or the medium of its growth.
Antibodies or Fc fusión proteins generated in CHO cells are fucosylated by fucosyltransferase activity.
Synthetic or recombinant fucosylated Oligosaccarides for use in the treatment of infections.
In some embodiments, the antibody is highly fucosylated.
Cell containing systems for the synthesis of fucosylated oligosaccharides may include recombinantly modified host cells.
Two oligosaccharides were abundantly found in goat 's milk - fucosylated and sialylated.
In Vivo Example Fucosylated HSCs exhibit enhanced engraftment in bone marrow in vivo.
Human IgG1 antibody is a highly fucosylated glycoprotein.
The fucosyllactose is a fucosylated oligosaccharide ( that is to say an oligosaccharide having a fucose residue ).
The antibody according to claim 1, wherein the antibody is partially fucosylated.
In a specific embodiment, fucosylated glycans are identified by mass spectroscopy.
In some embodiments, at least one heavy chain of the antibody is fucosylated.
Method for producing fucosylated oligosaccharides comprising the steps of,.
A particular compound of interest is GDP-fucose which is used as a precursor to synthesize fucosylated oligosaccharides.
In particular, two sulfated, fucosylated and sialylated glycoproteins have been identified.
The antibody for use according to claim 4, wherein said antibody is not substantially fucosylated.
Biantennary, sialylated, galactosylated and fucosylated glycans were also evidenced.
Alternatively, fucosylated oligosaccharides may be produced by chemical synthesis from lactose and free fucose.
Chapter 2 describes a more specific topic, involving fucosylated chondroitin sulfate found in sea cucumbers.
The fucosylated and non-fucosylated structures were determined and the integrated peak areas were quantified.
In particular, the modified binding protein is less fucosylated than the unmodified binding protein.
In an embodiment, the non-fucosylated antibody exhibits greater effector function than a corresponding fucosylated antibody.
Essentially more sialylated, more branched and less fucosylated than said second glycoprotein, or.
In one disclosure, the non-fucosylated antibody exhibits more efficacious therapeutic properties than a corresponding fucosylated antibody.
Thus, the invention features an efficient and economical use or method for producing fucosylated oligosaccharides.
In a composition of a " partially fucosylated antibody " only part of the oligosaccharides comprise fucose.
The composition of the higher molecular weight material was consistent with fucosylated complex-type oligosaccharides.
A method of producing a fucosylated carbohydrate in a single reaction mixture comprising the steps of,.
The treatment with sialidase confirmed the presence of both mono and bisialylated, biantennary, fucosylated structures.
The proportion of non-core fucosylated to core fucosylated antibody produced from each media was similar.
