Examples of 'genomic instability' in a sentence
Meaning of "genomic instability"
Genomic instability refers to the tendency of the genetic material in a cell to undergo changes or mutations, leading to an increased risk of various health conditions such as cancer
How to use "genomic instability" in a sentence
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genomic instability
The resulting genomic instability directly contributes to carcinogenesis.
These two phenomena are a reflection of high genomic instability.
This genomic instability may be caused by several factors.
Hypoxia induces an increase of genomic instability.
The genomic instability after stress is less pronounced in trained rats.
These two phenomena reflect a major genomic instability.
Nicotinamide increases genomic instability and shortens yeast life span.
Is we know that in cancer you tend to see genomic instability.
Genomic instability was proposed as the enabling characteristic of the hallmarks of cancer.
Cancer genetics and genomic instability.
The result is genomic instability which can lead to the development of cancers.
Molecular assessment for genomic instability.
This may be due to genomic instability or to the disruption of cellular metabolic processes.
His research interests include studying genomic instability in aging.
The increasing importance of genomic instability on cancer progression has been emphasized in recent years.
See also
The detection of such a difference is indicative of genomic instability within the sample.
Radiation-induced genomic instability is observed in cells long after irradiation.
A mammalian model of genomic instability.
Their direct repression by Engrailed could be part of a general protective activity against genomic instability.
Tumors are known to exhibit significant genomic instability and heterogeneity.
Genomic instability results from these bystander and delayed effects,.
The introduction of genomic instability.
Generally, genomic instability defines a broad class of disruptions in genomic nucleotide sequences.
Mechanisms of genomic instability.
Virus widely used in gene therapy research yields important clues to genomic instability.
This first step enables a potential genomic instability in the natural state to be identified.
The Commission sought more information about genomic instability.
Method of monitoring genomic instability using 3d microscopy and analysis.
A prominent characteristic of malignant phenotype is the propensity for genomic instability and uncontrolled growth.
In some embodiments, the genomic instability may lead to chromosome translocations.
Absence of cytosolic SOD causes a dramatic increase in mutagenesis and genomic instability.
DNA damage is the leading source of genomic instability and a cause of carcinogenesis.
In some embodiments, polyploidy is associated with genomic instability.
Do these results explain the genomic instability present in different types of cancers?
The accumulation of ROS increases genomic instability.
Accordingly, various aspects of genomic instability have been proposed as reliable markers for disease.
This effect is termed " induced genomic instability.
Inhibiting genomic instability may comprise reducing micronuclei formation and / or hyper-recombination.
Autophagy is a degradation process limiting genomic instability and cancer initiation.
A statistically-significant difference between the two quantitative amounts is indicative of genomic instability.
Aneuploidy could become the driving force of genomic instability and cancer progression.
Genomic instability is associated, for example, with a significant risk of cancer and degenerative diseases.
This first step makes it possible to identify possible genomic instability in the spontaneous state.
Such genomic instability indicates the possibility of cancerous or pre-cancerous cells in the sample.
Nor are they tumor cell lines with their inherent genomic instability and dysregulated gene expression.
The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability.
Besides, they promote genomic instability and the accumulation of mitotic defects contributing to malignant transformation.
For example, the intermingling of genetic material is indicative of genomic instability.
DNA damage and genomic instability appear to be the basic causes of sporadic ( non-familial ) cancer.
This maintenance methyltransferase, then the cells exhibit genomic instability.
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