Examples of 'genomic locus' in a sentence
Meaning of "genomic locus"
genomic locus: This term refers to a specific physical location on a chromosome where a particular gene or genetic marker is situated. It is commonly used in genetics and molecular biology to denote the position of genes in the genome
How to use "genomic locus" in a sentence
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genomic locus
The homologous sequences are specific to a single genomic locus.
In one embodiment the target genomic locus is in the genome of the cell.
Such methods can result in disruption of the target genomic locus.
Any given genomic locus can comprise at least two nucleic acid bases.
The target sequence can be at or near the genomic locus of interest.
Below is shown the genomic locus with each exon defined as a small box.
The present invention allows for modifying a target genomic locus on a chromosome in a cell.
The BMVSE genomic locus has been positioned to chromosome A of tobacco.
Methods and compositions are disclosed for enhancing homologous recombination at a target genomic locus in a cell.
A genomic locus may be defined by genomic coordinates, by name, or using a symbol.
A very interesting use of the hybrid meganuclease is for targeting a particular genomic locus of interest.
In an embodiment, the plasmid includes a genomic locus used for integrating a polynucleotide.
Comparing the result to a control cell with undamaged DNA genomic locus.
It targets a specific site of the CFTR genomic locus to be nicked or cleaved.
Some such methods result in bi-allelic modification of the target genomic locus.
See also
PCR strategy to amplify specific genomic locus for each cell line.
Figure 29 depicts two probe sets for identifying various alleles of the same genomic locus.
Alternatively, methylation of a genomic locus may be silent.
In one example, the insert polynucleotide can comprise any human or non-human genomic locus.
A method for targeted modification of a genomic locus of interest in a pluripotent rat cell, comprising,.
A prokaryotic cell comprising the insert nucleic acid at the target genomic locus can be selected.
In specific embodiments, the humanized genomic locus is capable of being transmitted through the germline.
In one embodiment, the target locus is a genomic locus.
Alternatively, the mutant allele of a genomic locus may contain a nucleotide substitution that is silent.
In another embodiment, a genetically modified rat comprising a humanized genomic locus is provided.
The deletion of the genomic locus of the transcriptional factor PrfA renders the mutant non-pathogen.
Cells The various methods and compositions described herein employ a genomic locus targeting system in a cell.
In specific embodiments, the genomic locus of interest comprises a target locus of a “ rat nucleic acid ”.
This resulted in a sequence of most of the genomic locus of tomato eIF4E.
A " type " for a genomic locus ( marker ) corresponds to specific attributes for a locus across tissue types.
In one embodiment, a method for modifying a target genomic locus in a cell is provided.
In another embodiment, the target genomic locus is on extrachromosomal DNA within the cell.
In some methods, the modified eukaryotic cell is hemizygous at the genomic locus of interest.
In an embodiment, the genomic locus is the BRAF gene.
Method according to claim 33, wherein said targeting locus is a genomic locus.
A method for modifying a target genomic locus in a mammalian cell, comprising,.
In another embodiment, a genetically modified non-human animal, comprising a humanized genomic locus is provided.
A method for modifying a target genomic locus in a human induced pluripotent stem cell ( hiPSC ), comprising,.
In another example, a double targeting method for modifying a target genomic locus in a cell is provided.
Clones containing IL-22RA genomic locus were identified and characterized.
All1-fusion proteins bind to EphA7 genomic locus.
The method of claim 1, wherein the genomic locus is a neutral site.
Figure 5 is a schematic of the human genomic locus for CPSI ;.
The method of Claim 14, wherein the plasmid includes a genomic locus used for integrating a polynucleotide.
Once merged, a consensus sequence can be called at a given genomic locus among the genomic loci.
RAAV vector can be designed to any target genomic locus and perform e . g.
The template DNA for each bead set represents a genomic locus listed in FIG . 9.
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