Examples of 'histone acetylation' in a sentence
Meaning of "histone acetylation"
histone acetylation - Histone acetylation is a biochemical process that involves the addition of acetyl groups to histone proteins, which are involved in packaging and regulating the structure of DNA in cells. This modification can impact gene expression, chromatin structure, and various cellular processes, playing a critical role in epigenetic regulation and cell function
How to use "histone acetylation" in a sentence
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histone acetylation
Histone acetylation is also an important process in transcription.
Discovery of the function of histone acetylation.
Histone acetylation influences chromatin structure in several ways.
Histone acetyltransferase catalyses histone acetylation.
Histone acetylation and deacetylation are catalyzed by multisubunit complexes.
Chromatin remodeling is influenced by histone acetylation and dna methylation.
Histone acetylation is known to be involved with modulation of transcription.
See also histone acetylation.
Histone acetylation and deacetylation are essential parts of gene regulation.
One of the most studied postranslational modification of histones is histone acetylation.
Histone acetylation assay.
It is present in protein complexes involved in histone acetylation and chromatin assembly.
Histone acetylation and deacetylation has long been linked to transcriptional control.
Histone deacetylase inhibitors alter the histone acetylation profile of chromatin.
Histone acetylation plays a key role in the regulation of eukaryotic gene expression.
See also
In regions of high transcriptional activity a high degree of histone acetylation can be found.
Imbalances in the levels of histone acetylation are associated with a wide variety of brain disorders.
The general mechanism of action of this molecule consists in inhibition of histone acetylation.
Histone acetylation causes nucleosomes and nucleosomal arrangements to behave with altered biophysical properties.
The two changes epigenetic most studied are dna methylation and histone acetylation.
The dynamic equilibrium between histone acetylation and deacetylation is essential for normal cell growth.
HAT activators are a viable approach to enhance histone acetylation.
The inventors examined whether histone acetylation occurred vÃa HDAC inhibition.
Histone acetylation is also involved in histone and DNA methylation regulation.
Increased gene expression following increased histone acetylation is an expected effect of an HDAC inhibitor.
In general, histone acetylation is linked to transcriptional activation and associated with euchromatin.
Scientists were able to demonstrate that GnRH induces histone acetylation at the LH gene promoter.
HATs facilitate histone acetylation and are thus believed to be transcriptional activators.
Both HDAC inhibitors and psychostimulants increase global levels of histone acetylation in NAc.
HBx also alters histone acetylation that can affect gene expression.
In other embodiments, the compound increases histone acetylation.
Methylation and histone acetylation states of STAR elements and of the adjacent transgenes.
They found that 7 days of nicotine treatment significantly increases histone acetylation.
Alterations in histone acetylation and DNA methylation occur in various genes influencing prostate cancer.
Inhibitors were also identified with improved potency in cell-based studies of histone acetylation.
Among these modifications, histone acetylation is the most studied.
Conversely, histone acetylation leads to relaxed nucleosomal structures, giving rise to a transcriptionally permissive chromatin state.
We then tested if YF2 increases histone acetylation in mouse hippocampus.
Histone acetylation / deacetylation alters chromosome structure and affects transcription factor access to DNA.
Figure 4 shows that DAC compounds reduce histone acetylation.
In addition, the level of histone acetylation when measured was significantly elevated relative to controls.
Thus, the Nut factor is the main element of the histone acetylation wave.
Example 6 . Methylation and histone acetylation states of STAR elements and of the adjacent transgenes.
The main strategy that is currently used to up-regulate histone acetylation involves HDAC inhibitors.
Histone acetylation assay, Western blot will be performed from snap-frozen in liquid nitrogen hippocampi.
Without being bound by theory, changes in histone acetylation play an important role in AD.
Histone acetylation and deacetylation is catalysed by histone acetyltransferases ( HATs ) and histone deacetylases ( HDACs ).
These modifications, which include DNA methylation, histone acetylation and histone methylation, are disregulated in tumors.
The presence of acetyl L-carnitine increased NGF-induced histone acetylation.
FIG . 28 is a schematic of histone acetylation and the role of HATs in such.
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Examples of using Acetylation
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Acetylation leads to the disruption of nucleosome structure
This makes an acetylation plant more expensive
Acetylation by acetic anhydride in the presence of pyridine
Examples of using Histone
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Histone acetylation is also an important process in transcription
The inhibitor inhibits histone methylase activity
Histone modifications modulate the packing of chromatin
