Examples of 'hmg-coa reductase inhibitor' in a sentence
Meaning of "hmg-coa reductase inhibitor"
HMG-CoA reductase inhibitors are a class of medications commonly used to lower cholesterol levels in the blood
How to use "hmg-coa reductase inhibitor" in a sentence
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hmg-coa reductase inhibitor
Simvastatin is an HMG-CoA reductase inhibitor or statin.
Simvastatin is known to be a compound of use as an HMG-CoA reductase inhibitor.
Suitably the HMG-CoA reductase inhibitor is a statin.
Stabilized pharmaceutical compositions comprising an HMG-CoA reductase inhibitor compound.
Wherein said HMG-CoA reductase inhibitor is cerivastatin.
A pharmaceutical composition as claimed in claim 5 which is useful as an HMG-CoA reductase inhibitor.
The HMG-CoA reductase inhibitor is provided in a nonpolymeric carrier.
In certain such embodiments the HMG-CoA reductase inhibitor is a statin.
An HMG-CoA reductase inhibitor selected from pitavastatin or a salt thereof.
This composition comprised the HMG-CoA reductase inhibitor composition.
An HMG-CoA reductase inhibitor selected from pitavastatin or a salt thereof, and.
Preferably, the additional compound is a HMG-CoA reductase inhibitor or antihypertensive agent.
Any HMG-CoA reductase inhibitor may be used in the combination aspect of this invention.
According to another preferred embodiment, the HMG-CoA reductase inhibitor is a statin.
If treatment with an HMG-CoA reductase inhibitor is indicated, pravastatin or fluvastatin is recommended.
See also
Previous history of muscular toxicity with another HMG-CoA reductase inhibitor or fibrate.
If treatment with a HMG-CoA reductase inhibitor is indicated, pravastatin or fluvastatin is recommended.
The coating also comprises a carrier for the HMG-CoA reductase inhibitor.
An immediate release HMG-CoA reductase inhibitor component in microparticulate form ; and.
This results in acceptably low rates of degradation of the HMG-CoA reductase inhibitor.
In a specific embodiment, the HMG-CoA reductase inhibitor is provided in a nonpolymeric carrier.
The coating composition includes an effective amount of the HMG-CoA reductase inhibitor.
In an embodiment, the HMG-CoA reductase inhibitor is selected from lovastatin or simvastatin.
Composition for inhibiting inflammation comprising hyaluronic acid and a hmg-coa reductase inhibitor.
In another embodiment, the HMG-CoA reductase inhibitor composition is in the form of multiparticulates.
According to another preferred embodiment, the kit further comprises an HMG-CoA reductase inhibitor.
In an embodiment, the HMG-CoA reductase inhibitor is selected from lovastatin and simvastatin.
The composition showed acceptable amounts of chemical degradation of the HMG-CoA reductase inhibitor.
Eluting a fraction containing HMG-CoA reductase inhibitor with a solvent mixture comprising,.
In another embodiment, the coating composition comprises more than one HMG-CoA reductase inhibitor.
In a preferred embodiment, the HMG-CoA reductase inhibitor composition comprises a stabilizing agent.
Statins are a class of drugs that can lower cholesterol and act as HMG-CoA reductase inhibitor.
Mevastatine is an HMG-CoA reductase inhibitor which blocks the synthesis of farnesyl metabolic precursors.
The pharmaceutical combination composition according to item 8 wherein HMG-CoA reductase inhibitor is fluvastatin sodium.
In one embodiment, the HMG-CoA reductase inhibitor composition is in the form of a compressed tablet.
It is preferred that the coating also comprise a carrier for the HMG-CoA reductase inhibitor.
A second layer comprising the HMG-CoA reductase inhibitor in a second polymeric carrier and.
The compound is preferably administered with a cholesterol biosynthesis inhibitor, particularly an HMG-CoA reductase inhibitor.
According to another preferred embodiment, an HMG-CoA reductase inhibitor is administered to the subject.
The coating substantially separates the solid amorphous dispersion from the HMG-CoA reductase inhibitor.
In some cases, the HMG-CoA reductase inhibitor is selected from lovastatin and simvastatin.
In another embodiment, the coating composition comprises a blend of HMG-CoA reductase inhibitor and a polymer.
In a preferred embodiment, the HMG-CoA reductase inhibitor used in the coating composition is cerivastatin.
A process for the large scale industrial purification of a crude HMG-CoA reductase inhibitor which comprises,.
In one aspect, the HMG-CoA reductase inhibitor is from a class of therapeutics commonly called statins.
Alternatively about two-thirds of the solvent mixture is removed to crystallize the HMG-CoA reductase inhibitor.
According to the present invention, the HMG-CoA reductase inhibitor is advantageously a compound selected from.
In a preferred embodiment, the unitary dosage form comprises a stabilizing agent for the HMG-CoA reductase inhibitor.
In presently preferred embodiments, the HMG-CoA reductase inhibitor is selected from lovastatin and simvastatin.
The solid amorphous dispersion within the granules are substantially separate from the HMG-CoA reductase inhibitor.
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Simvastatin is an HMG-CoA reductase inhibitor or statin
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