Examples of 'hmg-coa reductase' in a sentence
Meaning of "hmg-coa reductase"
HMG-CoA reductase is the enzyme responsible for the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis. It is often targeted by statin drugs to lower cholesterol levels in the body
How to use "hmg-coa reductase" in a sentence
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hmg-coa reductase
Interaction with HMG-CoA reductase inhibitors.
The HMG-CoA reductase inhibitor is provided in a nonpolymeric carrier.
The inhibitors are HMG-CoA reductase inhibitors.
An HMG-CoA reductase inhibitor selected from pitavastatin or a salt thereof.
Statins are inhibitors of HMG-CoA reductase enzyme.
Acceptance of HMG-CoA reductase inhibitors does not affect fat metabolism.
These compounds are inhibitors of HMG-CoA reductase.
Simvastatin is an HMG-CoA reductase inhibitor or statin.
They also have inhibitory activity on HMG-CoA reductase.
Regulation of HMG-CoA reductase by covalent modification.
A process for preparing intermediates of HMG-CoA reductase inhibitors.
Suitably the HMG-CoA reductase inhibitor is a statin.
This step is catalyzed by the enzyme HMG-CoA reductase.
The degradation of HMG-CoA reductase is tightly controlled.
Simvastatin is known to be a compound of use as an HMG-CoA reductase inhibitor.
See also
Wherein said HMG-CoA reductase inhibitor is cerivastatin.
Such a mechanism is complementary to that of HMG-CoA reductase inhibitors.
Statins inhibit HMG-CoA reductase within the mevalonate pathway.
As with other statins, atorvastatin is a competitive inhibitor of HMG-CoA reductase.
Treatment with these HMG-CoA reductase inhibitors.
It works by blocking the activity of an enzyme called HMG-CoA reductase.
The specific activity of HMG-CoA reductase was also calculated.
An HMG-CoA reductase inhibitor selected from pitavastatin or a salt thereof, and.
Stent coatings containing HMG-CoA reductase inhibitors.
Examples of HMG-CoA reductase inhibitors include the family of statins.
Other preferred compounds are HMG-CoA reductase inhibitors.
Additional HMG-CoA reductase inhibitors include rosuvastatin and pitavastatin.
In certain such embodiments the HMG-CoA reductase inhibitor is a statin.
Additional HMG-CoA reductase inhibitors include rosuvastatin and pitavostatin.
This composition comprised the HMG-CoA reductase inhibitor composition.
The mammalian genome contains a single gene encoding HMG-CoA reductase.
Statins inhibit HMG-CoA reductase from catalyzing this conversion.
Stabilized pharmaceutical compositions comprising an HMG-CoA reductase inhibitor compound.
If treatment with an HMG-CoA reductase inhibitor is indicated, pravastatin or fluvastatin is recommended.
Yeast cells contain two genes encoding HMG-CoA reductase.
If treatment with a HMG-CoA reductase inhibitor is indicated, pravastatin or fluvastatin is recommended.
Pravastatin is also a member of the family of HMG-CoA reductase inhibitors.
For decades, HMG-CoA reductase inhibitors have been used to treat hyperlipidemia.
Planar chemical structures of representative HMG-CoA reductase inhibitors are shown below,.
Other HMG-CoA reductase inhibitors should be considered such as pravastatin, fluvastatin or rosuvastatin.
Preferably, the additional compound is a HMG-CoA reductase inhibitor or antihypertensive agent.
Statins are a class of compounds that inhibit the enzyme HMG-CoA reductase.
An immediate release HMG-CoA reductase inhibitor component in microparticulate form ; and.
Interactions can not be excluded with other HMG-CoA reductase inhibitors.
Statins inhibit HMG-CoA reductase in their dihydroxy open acid form.
Synthesis of cholesterol by the liver is suppressed in the HMG-CoA reductase pathway.
In a specific embodiment, the HMG-CoA reductase inhibitor is provided in a nonpolymeric carrier.
A pharmaceutical composition as claimed in claim 5 which is useful as an HMG-CoA reductase inhibitor.
The active site of action of HMG-CoA reductase inhibitors is the liver.
Other HMG-CoA reductase inhibitors will be known to those skilled in the art.
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Interaction with HMG-CoA reductase inhibitors
Since increased concentrations of HMG-CoA
Simvastatin is an HMG-CoA reductase inhibitor or statin
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A reductase is an enzyme that catalyzes a reduction reaction
Reduced unspecific aldose reductase specific activity
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