Examples of 'humanised antibodies' in a sentence
Meaning of "humanised antibodies"
Humanised antibodies are monoclonal antibodies that have been modified to be more similar to antibodies produced naturally by humans, reducing the risk of immune reactions when used as therapeutics
How to use "humanised antibodies" in a sentence
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humanised antibodies
Chimeric or humanised antibodies can thus be used.
This has led to the development of humanised antibodies.
Humanised antibodies can be prepared by conventional procedures.
Methods for forming humanised antibodies by random mutagenesis.
The invention is typically applicable to the production of humanised antibodies.
Both humanised antibodies showed equivalent bioactivity.
Recombinant human or humanised antibodies.
Chimaeric humanised antibodies represent another aspect of the invention.
The present invention relates to chimeric antibodies as well as to humanised antibodies.
Methods for making humanised antibodies are known in the art.
Antibodies according to the present invention also include chimaeric or humanised antibodies.
Humanised antibodies have a greater degree of human peptide sequences than do chimeric antibodies.
His fundamental discoveries later make possible the production of humanised antibodies.
Further examples include chimeric or humanised antibodies against various tumour cell marker antigens.
The prior art discloses several ways of producing such humanised antibodies.
See also
Humanised antibodies were developed to counter the immune responses seen with murine and chimeric antibodies.
The present invention relates to antibodies and in particular to humanised antibodies and their preparation.
The invention also provides humanised antibodies wherein the antibody light chain is a kappa light chain.
In a specific embodiment, the antibodies are humanised antibodies.
The resulting chimeric or humanised antibodies to LMA should be particularly effective in inducing ADCC.
In one embodiment, the antibodies recovered are human or humanised antibodies.
Chimeric and Humanised Antibodies Chimeric antibodies are typically produced using recombinant DNA methods.
In one embodiment, the separated antibodies are human or humanised antibodies.
Humanised antibodies recognising human or murine a9 integrin.
Furthermore, the antibodies and fragments thereof may be humanised antibodies.
Examples of humanised antibodies include chimeric or CDR-grafted antibodies.
Non-human transgenic animals expressing humanised antibodies and use therof.
Humanised antibodies include chimeric antibodies and CDR-grafted antibodies.
Non-human transgenic animals expressing humanised antibodies and use thereof.
Humanised antibodies may be useful for reducing immunogenicity of an antibody ( or antibody fragment ).
Anti-human milk fat globule humanised antibodies and processes for their production.
Humanised antibodies are then selected by e.g. panning of the phage displayed antibody library.
Polynucleotide reagents, and vectors suitable for encoding the humanised antibodies are also disclosed.
Anti-mag humanised antibodies and their uses for treating stroke.
Furthermore, the antibodies and fragment thereof may be chimeric antibodies, CDR-grafted antibodies or humanised antibodies.
Polyclonal, monoclonal and humanised antibodies specific for the complexes described herein may be prepared.
Allergy to Chinese hamster ovary ( CHO ) cell products or other recombinant human or humanised antibodies.
Until now, all of the humanised antibodies have contained a light chain of the kappa type.
Hypersensitivity to Chinese Hamster Ovary ( CHO ) cell products or other recombinant human or humanised antibodies.
Anticoagulant humanised antibodies against factor IX, for use in the treatment of thrombosis.
The present inventors have provided new anti-CSF-1R antibodies, including humanised antibodies.
Humanised Antibodies In another embodiment, the antibody is humanised.
Moreover, antibodies of the present invention include chimeric, single chain, and humanised antibodies.
Methods for making humanised antibodies are described in, for example, US Patent No.
Particularly preferred examples include chimaeric or humanised antibodies against CDw52 . CD4 and CD23 antigen.
Anti-IL-18 humanised antibodies were added at various dilutions.
The disclosure relates to fully human, or humanised antibodies that induce antibody-directed cell-mediated cytotoxicity ( ADCC ).
Bound humanised antibodies were detected using anti-humanIgG Fc specific peroxidase conjugate ( Sigma A0170 ).
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