Examples of 'hydroxamic' in a sentence
Meaning of "hydroxamic"
hydroxamic: containing the functional group -CONHOH
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- Describing any of several classes of compounds derived from oxoacids by replacing -OH by -NHOH; the N-hydroxy amides
How to use "hydroxamic" in a sentence
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hydroxamic
This invention relates to hydroxamic acid derivatives.
Isoxazole hydroxamic acid compounds as LpxC inhibitors.
Process for the preparation of hydroxamic acids.
Such hydroxamic acids are commercially available.
All these references relate to sulfonamide hydroxamic acids.
Hydroxamic acid derivatives and pharmaceutical compositions thereof.
The invention provides sulfonyl hydroxamic acid derivatives.
Hydroxamic acids are commonly synthesized from their corresponding esters.
Hadacidin is the simplest known naturally occurring hydroxamic acid.
Hydroxamic acids are also preferred.
The present invention relates to arylsulfonylamino hydroxamic acid derivatives.
Hydroxamic acids and hydroxamates are known to be useful as metal chelators.
The present invention is concerned with hydroxamic acid derivatives.
But the hydroxamic acid derivative is usually administered to an adult ca.
Linkages with carboxylic acids are typically referred to as carbohydrazides or as hydroxamic acids.
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The hydroxamic acids are solids.
The salt upon acidification or dilution turns to fatty hydroxamic acid.
The free hydroxamic acids may be liberated as previously described.
Some compounds only bound to stromelysin in the presence of hydroxamic acid.
Hydroxamic acid and derivatives.
This invention relates to the use of hydroxamic acid derivatives as antibacterial agents.
Hydroxamic acids have also been investigated for reprocessing of irradiated fuel.
All of these reported inhibitors contain a hydroxamic acid zinc binding group.
The hydroxamic acid group is a common motif in zinc metalloprotease inhibitors.
This compound is constituted by a polymer bearer of hydroxamic groups attached to a linear hydrocarbon chain.
The hydroxamic acid compounds in these references have an obligatory peptide backbone.
Specific examples of such derivatives include nicotinuric acid and nicotinyl hydroxamic acid.
Certain of the hydroxamic acid derivatives of the present invention are preferred.
The carboxylic acid is then transformed into the hydroxamic acid by the usual procedures.
Some derivatives of hydroxamic acid which inhibit histone deacetylases are known.
These salts also readily form in aqueous solutions of the carboxylic and hydroxamic acids.
Hydroxamic acid formed is converted into an iron complex in the presence of trichloroacetic acid.
The lower the pKa of the hydroxamic acid moiety the more stable the complex.
Hydroxamic acids are a class of chemical compounds in which a hydroxylamine is inserted into a carboxylic acid.
Nonlimiting specific examples of suitable niacinamide derivatives include nicotinuric acid and nicotinyl hydroxamic acid.
The term also includes hydroxamic acid derivates of the compounds of the present invention.
Any of the above anionic flocculants may be further functionalized with pendant hydroxamic acid groups.
The hydroxamic acid derivatives which have lipoxygenase inhibitory activity are disclosed in JP.
It is remarkable that in the presence of a hydroxamic polymer Ex.
These values are equivalent to those of hydroxamic acids as a conventionally known typical urease inhibitor K.
Most preferred synthetic MMP inhibitors are organic molecules based on hydroxamic acid.
The synthesis of the requisite hydroxamic acids IV can be accomplished by several known methods.
The enzyme was also activated using APMA and was then purified over a hydroxamic acid column.
Previous Disclosures Polymers containing hydroxamic acid functional groups have been known in the art.
This olefin may then be used in Scheme B to yield hydroxamic acids.
Higher alkyl hydroxamic acids are less water-soluble.
Esters can be converted to isocyanates through intermediate hydroxamic acids in the Lossen rearrangement.
A hydroxamic acid derivative according to claim 7 or a pharmaceutically acceptable salt thereof ;.
Scheme I also illustrates hydroxamate formation to prepare the hydroxamic acid products of this invention.
Free acids, free hydroxamic acids, and cyclopropylmethyl hydroxamates are grouped together.
