Examples of 'immunoglobulin sequence' in a sentence
Meaning of "immunoglobulin sequence"
immunoglobulin sequence: The unique order of amino acids in an immunoglobulin protein, which plays a critical role in the immune system
How to use "immunoglobulin sequence" in a sentence
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immunoglobulin sequence
A respective amino acid sequence that is an immunoglobulin sequence.
The human immunoglobulin sequence is an immunoglobulin heavy chain sequence.
Fusion partners may be linked to the immunoglobulin sequence vía a linker sequences.
The modified immunoglobulin sequence may be present at the endogenous mouse heavy chain immunoglobulin locus.
Suitable conjugate moieties include portions of immunoglobulin sequence that include the FcRn binding site.
Preferred polypeptides of the invention comprise an amino acid sequence derived from a human immunoglobulin sequence.
The TCR or immunoglobulin sequence can amplified using a primary and a secondary amplification step.
A convenient vector is one that encodes a functionally complete human CH or CL immunoglobulin sequence.
Such IgG immunoglobulin sequence can be purified efficiently on immobilized protein A.
The multimerization domains can interact vía an immunoglobulin sequence e . g.
In one embodiment, the immunoglobulin sequence is an immunoglobulin constant domain.
In a preferred embodiment, the linker comprises an immunoglobulin sequence.
In one aspect, the human immunoglobulin sequence is a light chain sequence.
Preferably, the immunoglobulin domain is a human immunoglobulin sequence.
In one aspect, the human immunoglobulin sequence is a heavy chain sequence.
See also
immunoglobulin molecules
immunoglobulin preparations
immunoglobulin superfamily
immunoglobulin variable
immunoglobulin preparations
immunoglobulin superfamily
immunoglobulin variable
In some aspects, the first sequence of interest is an immunoglobulin sequence.
The non-mouse immunoglobulin sequence may comprise a human immunoglobulin sequence.
In some disclosures, the first sequence of interest is an immunoglobulin sequence.
The immunoglobulin sequence typically, but not necessarily, is an immunoglobulin constant domain.
The bispecific molecule of claim 18 further comprising an immunoglobulin sequence.
In one aspect, the human immunoglobulin sequence is an immunoglobulin light chain sequence.
A " consensus framework " of an immunoglobulin refers to a framework region in the consensus immunoglobulin sequence.
In one embodiment, the human immunoglobulin sequence is an immunoglobulin constant domain sequence.
A " consensus framework " refers to the framework region in the consensus immunoglobulin sequence.
The immunoglobulin sequence preferably, but not necessarily, is an immunoglobulin constant domain.
In a preferred embodiment, the linker comprises an immunoglobulin sequence preferably resulting in a bispecific immunoadhesin.
In some embodiments, the sequence data is obtained by searching publicly available immunoglobulin sequence listings.
In one embodiment, the human immunoglobulin sequence is an immunoglobulin heavy chain sequence.
The monoclonal antibody of claim 6, wherein the heterologous amino acid sequence comprises an immunoglobulin sequence.
In one aspect, the non-mouse immunoglobulin sequence comprises a human immunoglobulin sequence.
In one embodiment, the non-human locus is modified with at least one human immunoglobulin sequence.
In one embodiment, the non-mouse immunoglobulin sequence comprises a human immunoglobulin sequence.
The chimeric molecule of claim 47 wherein said heterologous amino acid sequence comprises an immunoglobulin sequence.
In a specific aspect, the at least one non-mouse immunoglobulin sequence is a human immunoglobulin sequence.
In various aspects, the sequence that encodes ADAM6 activity is contiguous with a human immunoglobulin sequence.
In a specific embodiment, the at least one non-mouse immunoglobulin sequence is a human immunoglobulin sequence.
The immunoglobulin sequence typically, but not necessarily, is an immunoglobulin constant domain ( Fc region ).
The chimeric molecule may comprise an Apo-2 polypeptide fused to an immunoglobulin sequence.
In one aspect, the immunoglobulin sequence comprises a single VH gene segments.
In another embodiment, the chimeric molecule comprises an Apo-2 polypeptide fused to an immunoglobulin sequence.
In one embodiment, the immunoglobulin sequence comprises a single VH gene segments.
Amino acid sequence according to any of aspects 49 to 59, that is a humanized immunoglobulin sequence.
In one aspect, the immunoglobulin sequence comprises one or more VI gene segments.
The method of any of claims 14 to 16, wherein said heterologous linker comprises an immunoglobulin sequence.
In one embodiment, the immunoglobulin sequence comprises one or more VH gene segments.
The immunoglobulin sequence preferably, but not necessarily, is an immunoglobulin constant domain ( Fc region ).
In one embodiment, the human immunoglobulin sequence comprises one or more JH gene segments.
The immunoglobulin sequence is the CH2 and CH3 immunoglobulin domains of IgG.
In one embodiment, the human immunoglobulin sequence comprises one or more DH gene segments.
In one embodiment, the immunoglobulin sequence is obtained from IgG1 or IgG3.
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