Examples of 'inactive metabolites' in a sentence

Meaning of "inactive metabolites"

inactive metabolites - this phrase is used in the context of pharmacology and biochemistry to describe the byproducts or breakdown products of a substance that are not biologically active. It is often referred to in discussions about drug metabolism and elimination from the body

How to use "inactive metabolites" in a sentence

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inactive metabolites
Of the inactive metabolites is present at low concentrations.
Fentanyl is metabolized in the liver to inactive metabolites.
Most of the inactive metabolites are excreted.
Ketoconazole is extensively metabolised to a large number of inactive metabolites.
The inactive metabolites of the barbiturates are excreted as conjugates of glucuronic acid.
Fentanyl is metabolised into inactive metabolites in the liver.
Busulfan is metabolized via glutathione conjugation in the liver to inactive metabolites.
Fentanyl is metabolized into inactive metabolites in the liver.
Salicylic acid is eliminated by renal excretion and by biotransformation to inactive metabolites.
The remainder is inactive metabolites.
Antibodies could also be selected for reactivity to biologically inactive metabolites.
In systemic circulation only one of the inactive metabolites is present at low concentrations.
Biosynthesized from cholesterol and converted in liver into inactive metabolites.
Amoxicillin is partially metabolized to inactive metabolites and then rapidly excreted in urine.
A small portion of the administered dose is excreted in the urine as inactive metabolites.

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ISMN is metabolised to inactive metabolites including isosorbide and isosorbide glucuronide.
In the liver it is metabolized to inactive metabolites.
However, its inactive metabolites can stay in your system for a few days to 3 months.
It is sparingly metabolised in the liver to two inactive metabolites.
Gliclazide undergoes extensive metabolism to several inactive metabolites in human beings, mainly methylhydroxygliclazide and carboxygliclazide.
These medications are excreted in the urine as inactive metabolites.
Its primary inactive metabolites have in vivo serum half-lives of approximately 24 hours.
It is metabolized by the liver to inactive metabolites.
Although only inactive metabolites are excreted by the renal route, < Invented name > 10 mg /.
Morphine is glucorinated in inactive metabolites.
Clopidogrel is a prodrug and is metabolized to a pharmacologically active metabolite and inactive metabolites.
It is metabolized to inactive metabolites.
Lorazepam is highly protein bound and is extensively metabolized into pharmacologically inactive metabolites.
In the liver, demethylated, inactive metabolites are formed.
Metabolism Icatibant is extensively metabolized by proteolytic enzymes to inactive metabolites.
In addition to the active metabolite, inactive metabolites are formed.
The first two, of xanthine oxidase and thiopurine methyltransferase, produce inactive metabolites.
In addition to the active metabolite, biologically inactive metabolites are formed, incl.
To a large extent, it undergoes biotransformation in the liver with the formation of inactive metabolites.
It is extensively metabolized in the liver to inactive metabolites via CYP3A4.
Fluoxetine and sertraline produce active metabolites, while paroxetine is metabolized to inactive metabolites.
Receptor-based assays would ignore inactive metabolites.
They may also convert active nucleoside-based drugs into inactive metabolites.
Metabolism, Hepatic ; converted to inactive metabolites.
Etabolism, including results concerning possible genetic polymorphism, the formation of active and inactive metabolites.
About 70 % of the dose is excreted in the urine as inactive metabolites.
Second, MAbs can not distinguish between pharmacologically active and pharmacologically inactive metabolites.
Fentanyl is metabolized in the liver, with formation of inactive metabolites.
In the liver, it is demethylated with the formation of inactive metabolites.
These enzymes also convert active nucleoside-based cancer drugs into inactive metabolites.
Metabolism, Crisaborole is substantially metabolized into inactive metabolites.
In humans, the drug is metabolized primarily by N-dealkylation to norfentanyl and other inactive metabolites.
A mean of 90 % is bound to plasma proteins, and it has hepatic metabolism into inactive metabolites.
It is more than 90 % eliminated by biotransformation to N-dealkylated and hydroxylated inactive metabolites.
However, the incretins are normally rapidly degraded by DPP-4 into inactive metabolites.

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Examples of using Metabolites
Both metabolites were rapidly degraded to carbon dioxide
There are two major metabolites in human plasma
These metabolites appear to be pharmacologically inactive in man
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Examples of using Inactive
An active policy becomes inactive while it is copied
Then an inactive form of a toxic drug is administered
A person is said to be inactive in all other cases
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