Examples of 'kinase inhibition' in a sentence
Meaning of "kinase inhibition"
Kinase inhibition: The process of blocking or reducing the activity of enzymes known as kinases, which play a crucial role in various cellular processes
How to use "kinase inhibition" in a sentence
Basic
Advanced
kinase inhibition
Heterocyclic compounds useful for kinase inhibition.
Methods of determining kinase inhibition are well known in the art.
Novel approaches for ErbB receptor tyrosine kinase inhibition.
The cardiotonic benefit of kinase inhibition has also been studied.
Compounds and therapeutic use thereof for protein kinase inhibition.
The cardiotonic benefits of kinase inhibition has also been studied.
Those of ordinary skill would be surprised by the specificity of the kinase inhibition.
CaM kinase inhibition suppresses pacing induced inward current.
Heteroaryl compounds for kinase inhibition.
GPBP kinase inhibition enhances glucose consumption under increased extracellular glucose concentrations.
Applications of pyruvate kinase inhibition.
GPBP kinase inhibition also enhances glucose consumption under physiological extracellular glucose concentrations.
Furthermore compounds of this type have known physiological activities related to tyrosine kinase inhibition.
Methods for screening such compounds for ALK kinase inhibition are further described above.
CaM kinase inhibition also suppressed inward currents associated with DADs and intracellular calcium overload.
See also
Methods for screening such compounds for ROS kinase inhibition are further described above.
Second, kinase inhibition selectivity plays an important role.
These compounds thus exhibited EGFR kinase inhibition activity.
Tyrosine kinase inhibition can be determined using well-known methods.
Particularly, the compounds are useful for kinase inhibition.
To measure the protein kinase inhibition activity of the compounds, the following constructs were devised.
The in vitro inhibitory properties of compounds were determined using a p38 kinase inhibition assay.
In the alternative, the tyrosine kinase inhibition activity is determined according to the following method.
Various insoluble compounds, however, have exhibited significant kinase inhibition in in vitro testing.
The PDGF-R kinase inhibition assay was performed as described supra.
In particular, the invention relates to quinazoline derivatives which exhibit protein tyrosine kinase inhibition.
With such high dosing, side effects due to broad kinase inhibition can become a serious problem.
In particular, the invention relates to a quinazoline derivative which exhibits protein tyrosine kinase inhibition.
KDR or Raf kinase inhibition exerts antiangiogenic and / or antiproliferative effect in tumor cell lines.
These data suggest that SC-1 derived from sorafenib does not affect kinase inhibition.
The IC50 values of the KDR kinase inhibition activity are calculated using XLfit software.
Figure 13B sets forth a schematic representation of the approach toward selective protein kinase inhibition described here.
Methods for screening such compounds for ALK kinase inhibition are further described above . Indirect Inhibitors.
PK / PD analysis demonstrated a dose dependent relationship between Compound 1 exposure and mTOR kinase inhibition.
Table 4B Kinase inhibition analysis of peptides.
The pharmaceutical composition of any of claims 3-6 wherein it is useful for protein kinase inhibition.
Kinase inhibition for a given compound was expressed as an IC50 value.
Accordingly, a Tie-2 receptor kinase inhibition approach has become a strategy of choice.
Representative results are shown in Table IV for EGFR, erbB2, and erbB4 tyrosine kinase inhibition.
For example, kinase inhibition can be determined using an IMAP ® assay ( Molecular Devices ).
Thieno [ 2,3-d ] pyridazine derivatives and therapeutic use thereof for protein kinase inhibition.
The CaM kinase inhibition experiments consisted of 4 periods ( Figure 1A ).
The latter protein increases in amount with the level of CDK5/p35 kinase inhibition.
The mechanism by which K-252a inhibits the activity of HMGB1 seems to be kinase inhibition.
You'll also be interested in:
Examples of using Inhibition
Show more
Inhibition of activity with high concentrations of nutrients
Then the percentage inhibition should be calculated
Inhibition results in the regression of prostatic tumours
Examples of using Kinase
Show more
Creatine kinase can be checked if myalgias develop
Blood tests show elevated creatine kinase
Elevation of creatine kinase in blood is indicative of myositis
