Examples of 'metabotropic' in a sentence
Meaning of "metabotropic"
Metabotropic (noun): Relating to a type of receptor in cell membranes that does not have an intrinsic ion channel but may trigger metabolic changes within the cell upon binding with a signaling molecule
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- Describing a neurotransmitter or cell receptor whose action is mediated by metabolic functions (e.g. enzyme activation)
How to use "metabotropic" in a sentence
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metabotropic
Dynamic regulation of metabotropic glutamate receptor signaling.
A metabotropic glutamate receptor variant functions as a taste receptor.
Receptor fragments are portions of metabotropic glutamate receptors.
Role of metabotropic glutamate receptors in nociception.
Alkynyl derivatives as modulators of metabotropic glutamate receptors.
Metabotropic receptors do not have channels.
The fourth type is metabotropic and is called mGluR.
No metabotropic activity has been demonstrated for these compounds.
The fourth receptor is termed the metabotropic receptor.
Metabotropic receptors constitute another class.
Ionotropic and metabotropic receptors.
Metabotropic glutamate receptors and ligands in the central nervous system.
Receptor fragments are portions of metabotropic glutamate receptors or of calcium receptors.
The metabotropic glutamate receptors are classified pharmacologically into three groups.
Such binding agents are preferably modulators of a metabotropic glutamate receptor.
See also
Eight subtypes of metabotropic glutamate receptors have been cloned.
Dopamine receptors are metabotropic.
Both of these metabotropic receptors are distinguished by their reactivity to specific activators.
They have been shown to possess affinity for metabotropic glutamate receptors.
The majority of metabotropic glutamate receptors function in the form of homodimers.
Such surface receptors are characterized as either ionotropic or metabotropic glutamate receptors.
These uses of metabotropic glutamate receptor proteins are not meant to be limiting.
Amphetamines would thus remove an inhibiting effect due to metabotropic glutamate receptors.
Metabotropic glutamate receptors as novel targets for anxiety and stress disorders.
Muscarinic receptors are metabotropic and affect neurons over a longer time frame.
Preferably the identification method uses a recombinant chimeric metabotropic glutamate receptor.
Metabotropic responses occur in dopamine neurons through the regulation of the excitability of cells.
It also is concerned with fragments of metabotropic glutamate receptors and calcium receptors.
Metabotropic glutamate receptor agonists have been reported to have effects on various physiological activities.
Said three compounds were never disclosed in relation with metabotropic glutamate receptors.
This effect is relayed by a metabotropic receptor distinct from the conventional benzodiazepine receptors.
The subject of the present invention is a novel human metabotropic glutamate receptor.
Combinations of metabotropic glutamate receptor antagonists and their use in treating addictive disorders.
Additional heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists.
Metabotropic dopamine receptors are present both on spiny neurons and on cortical axon terminals.
The two main types of glutamate receptors are ionotropic receptors and metabotropic receptors.
Combination therapy with metabotropic glutamate receptor antagonists such as fenobam may also be useful.
Glutamate exerts its actions through both ionotropic and metabotropic glutamate receptors.
Inhibition of metabotropic glutamate receptor activation prevents one or more of these activities from occurring.
Chromone oxime derivative and its use as allosteric modulator of metabotropic glutamate receptors.
Metabotropic glutamate receptors have been implicated in a number of normal processes in the mammalian CNS.
Such agents can be used to treat patients by modulating metabotropic glutamate receptor activity.
Metabotropic receptors, are slow response receptors in postsynaptic cells.
As such they are useful for the treatment of conditions associated with metabotropic glutamate receptors.
In contrast, metabotropic receptors are associated with neuronal protection.
EAA receptors have been characterized as metabotropic or ionotropic.
Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain.
An exception is the ACPD receptor subtype which has the properties of a metabotropic receptor.
The parent compound exhibits affinity for metabotropic glutamate receptors and has an agonistic effect.
There are four different histamine receptors in mammals and they are all metabotropic GPCR receptors.
