Examples of 'metabotropic glutamate' in a sentence
Meaning of "metabotropic glutamate"
metabotropic glutamate: Metabotropic glutamate receptors are a type of receptor in the brain that are involved in regulating synaptic transmission. They play a role in various physiological functions such as learning and memory
How to use "metabotropic glutamate" in a sentence
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metabotropic glutamate
Dynamic regulation of metabotropic glutamate receptor signaling.
A metabotropic glutamate receptor variant functions as a taste receptor.
Receptor fragments are portions of metabotropic glutamate receptors.
Role of metabotropic glutamate receptors in nociception.
Alkynyl derivatives as modulators of metabotropic glutamate receptors.
Metabotropic glutamate receptors and ligands in the central nervous system.
Receptor fragments are portions of metabotropic glutamate receptors or of calcium receptors.
The metabotropic glutamate receptors are classified pharmacologically into three groups.
Such binding agents are preferably modulators of a metabotropic glutamate receptor.
Eight subtypes of metabotropic glutamate receptors have been cloned.
They have been shown to possess affinity for metabotropic glutamate receptors.
The majority of metabotropic glutamate receptors function in the form of homodimers.
Such surface receptors are characterized as either ionotropic or metabotropic glutamate receptors.
These uses of metabotropic glutamate receptor proteins are not meant to be limiting.
Amphetamines would thus remove an inhibiting effect due to metabotropic glutamate receptors.
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Metabotropic glutamate receptors as novel targets for anxiety and stress disorders.
It also is concerned with fragments of metabotropic glutamate receptors and calcium receptors.
Metabotropic glutamate receptor agonists have been reported to have effects on various physiological activities.
Preferably the identification method uses a recombinant chimeric metabotropic glutamate receptor.
Combinations of metabotropic glutamate receptor antagonists and their use in treating addictive disorders.
Said three compounds were never disclosed in relation with metabotropic glutamate receptors.
Combination therapy with metabotropic glutamate receptor antagonists such as fenobam may also be useful.
Additional heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists.
Inhibition of metabotropic glutamate receptor activation prevents one or more of these activities from occurring.
The subject of the present invention is a novel human metabotropic glutamate receptor.
Metabotropic glutamate receptors have been implicated in a number of normal processes in the mammalian CNS.
Glutamate exerts its actions through both ionotropic and metabotropic glutamate receptors.
Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain.
Chromone oxime derivative and its use as allosteric modulator of metabotropic glutamate receptors.
Also, metabotropic glutamate receptors are divided into three pharmacological groups.
Such agents can be used to treat patients by modulating metabotropic glutamate receptor activity.
The group 1 metabotropic glutamate receptor antagonists are an exciting near-term therapeutic possibility.
As such they are useful for the treatment of conditions associated with metabotropic glutamate receptors.
The metabotropic glutamate receptors ( mGluR ) have been pharmacologically divided into two subtypes.
The parent compound exhibits affinity for metabotropic glutamate receptors and has an agonistic effect.
The metabotropic glutamate receptors ( mGluR ) have been pharmacologically divided into three subtypes.
The compounds are ligands for the metabotropic glutamate receptors of group II.
Metabotropic glutamate receptors, that can modulate synaptic transmission, thus constitute promising therapeutic targets.
Preferably, use is made of a human metabotropic glutamate receptor.
Identification of metabotropic glutamate receptor-modulating agents facilitated by using a high-throughput screening system.
This first group are termed PI-linked metabotropic glutamate receptors.
Introducing said metabotropic glutamate receptor and a potential compound into an acceptable medium ; and.
It exerts its effect as an antagonist of the metabotropic glutamate receptor 5 mGluR5.
Metabotropic glutamate receptor 4 is a protein that in humans is encoded by the GRM4 gene.
Preferably, the agent can modulate metabotropic glutamate receptor activity.
The metabotropic glutamate receptors are G-protein-coupled receptors, activating intracellular signal transduction cascades.
Preferably, the method is used to identify a metabotropic glutamate receptor-modulating agent.
Metabotropic glutamate receptors are a family of seven transmembrane domain G-protein-coupled receptors ( GPCR ).
Diagnoses can be carried out using metabotropic glutamate receptor-binding agents.
The present invention provides compounds that selectively affect the negatively-coupled cAMP-linked metabotropic glutamate receptors.
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Examples of using Glutamate
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Your glutamate levels are about the same
Riluzole is proposed to act by inhibiting glutamate processes
Glutamate is one of the neurotransmitters in the brain
Examples of using Metabotropic
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Dynamic regulation of metabotropic glutamate receptor signaling
A metabotropic glutamate receptor variant functions as a taste receptor
Receptor fragments are portions of metabotropic glutamate receptors
