Examples of 'modified polynucleotide' in a sentence
Meaning of "modified polynucleotide"
A modified polynucleotide refers to an altered form of a nucleic acid (RNA or DNA) chain, often created in a laboratory setting through various chemical or genetic engineering techniques
How to use "modified polynucleotide" in a sentence
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modified polynucleotide
Said agents include modified polynucleotide sequences.
The modified polynucleotide may be obtained as indicated above.
Preferred molecules on an array are modified polynucleotide oligomers of the present invention.
Modified polynucleotide oligomers can be provided in various salt forms.
A preferred array element is a modified polynucleotide oligomer of the present disclosure.
The modified polynucleotide sequence may also be prepared by conventional techniques.
A variety of sugar moieties can be used to modify a modified polynucleotide of the present invention.
The modified polynucleotide generally encodes a polypeptide which has methylarginase activity.
The DNA recognition domain could also be a natural or modified polynucleotide.
The modified polynucleotide generally encodes a polypeptide which has aminopeptidase activity.
In some embodiments, a target polynucleotide is a modified polynucleotide.
The modified polynucleotide generally encodes a polypeptide which has xylanase activity.
Preferably, the polynucleotide of the present invention is a modified polynucleotide.
Modified polynucleotide oligomers can been used to regulate gene expression and in antisense gene therapy.
In some embodiments, a modified polynucleotide oligomer is radiolabeled.
See also
The modified polynucleotide generally encodes a polypeptide which has proline specific endoprotease activity.
Compositions, methods and kits comprising such modified polynucleotide oligomers are further provided.
The modified polynucleotide generally encodes a polypeptide which has IgG specific cysteine protease activity.
In another non-limiting example, a further modified polynucleotide oligomer comprises a sugar modification and a label.
The modified polynucleotide generally encodes a polypeptide which has B-glucanase activity.
In yet another non-limiting example, a further modified polynucleotide oligomer comprises a label and a base modification.
A preferred modified polynucleotide oligomer of the present invention is one that comprises a modified cytosine base.
In some embodiments, the present invention provides a duplex comprising a modified polynucleotide oligomer and a polynucleotide sequence.
In some embodiments, a modified polynucleotide oligomer is used as a primer for amplification.
In some embodiments, a modified polynucleotide oligomer is provided in a salt form.
In some embodiments, a modified polynucleotide oligomer of the invention is used as a primer.
In some embodiments, modified polynucleotide oligomers of the present invention are attached to an array.
In some embodiments, a modified polynucleotide oligomer of the present invention is attached to a bead.
In some embodiments, a modified polynucleotide oligomer comprises unnatural proportions of an atomic isotope.
In some embodiments, a modified polynucleotide oligomer comprises one or more phosphodiester linkages.
In a further example, a further modified polynucleotide oligomer comprises a backbone modification and a label.
In some embodiments, modified polynucleotide oligomers described herein comprise basic and / or acidic functionalities.
For example, a further modified polynucleotide oligomer comprises a sugar modification and a backbone modification.
In some embodiments, both the modified polynucleotide and the polynucleotide sequence are non-naturally occurring.
In some embodiments, a modified polynucleotide oligomer is a FRET probe.
In some embodiments, a modified polynucleotide oligomer comprises one or more nucleotides having an LNA sugar.
In some embodiments, a modified polynucleotide oligomer comprises a locked nucleic acid ( " LNA " ) sugar.
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Polynucleotide capable of selectively hybridizing to a polynucleotide as defined in a or b or c
