Examples of 'modified polypeptides' in a sentence
Meaning of "modified polypeptides"
Modified polypeptides: Refers to proteins that have been altered or manipulated from their original structure, often for scientific or medical purposes
How to use "modified polypeptides" in a sentence
Basic
Advanced
modified polypeptides
The term also refers to chemically modified polypeptides.
Modified polypeptides for use in this aspect of the methods are described herein.
Arrows indicate the regions that are deleted or replaced in the modified polypeptides.
Modified polypeptides having substantially similar function are also used for peptide therapy.
Also provided are pharmaceutical compositions comprising the modified polypeptides of the invention.
Among the modified polypeptides provided herein are those in which coagulation activity is increased.
These techniques have been applied to a variety of native polypeptides and to chemically modified polypeptides.
Such modified polypeptides may thereafter be analyzed to determine the effect of such modifications.
Administrations of the composition comprising modified polypeptides can be repeated to enhance the therapeutic outcome.
The modified polypeptides of the present invention will retain a substantial portion of their biological activity.
In specific embodiments such modified target DNA encodes modified polypeptides.
Compositions comprising modified polypeptides that exhibit large therapeutic ratios or indices are most preferred.
The amino acid sequences for two modified polypeptides Nos.
The modified polypeptides were diluted in RPMI and transferred to the wells of microtitre plates.
In the preferred embodiments of the invention the modified polypeptides and DNA sequences are human.
See also
The modified polypeptides may be formulated into a composition in a free base, neutral, or salt form.
The prior art also discloses the use of modified polypeptides for treating SLE.
Such modified polypeptides fall within the scope of the term " polypeptide " of the disclosure.
INTRODUCTION The field of this invention is modified polypeptides with improved pharmacokinetics.
Polypeptides include both unmodified, naturally-occurring polypeptides and modified polypeptides.
Modified DNA encoding such modified polypeptides is preferably derived by the methods of the invention.
The term “ polypeptide ” indicates proteins as well as modified polypeptides.
Preferably, compositions comprising modified polypeptides elicit minimal or no immune response from the patient.
Modified polypeptides ( including antibodies ) may retain the binding properties of unmodified molecules of the invention.
A method as claimed in claim 44 wherein said modified polypeptides are a modified antibiotic hydrolase.
Modified polypeptides can be produced, for instance, by amino acid substitution, deletion, or addition.
Nucleic acids, polypeptides, posttransiationally modified polypeptides and lipids and the like.
In a third aspect, the modified polypeptides are provided as a pharmaceutical composition ( as described below ).
Fig . 14 illustrates the stability and antigenicity of modified polypeptides.
Design of massive numbers of modified polypeptides is feasible, even for a relatively short reference polypeptide.
As stated above, polypeptide variants include, e.g., modified polypeptides.
Modified polypeptides with improved H 11 immunologic activity are preferred.
As stated above, polypeptide variants include, e . g ., modified polypeptides.
Such modified polypeptides can show, e.g., enhanced activity or increased stability.
The invention also provides modified polypeptides as set forth in claim 16 or claim 17.
Such modified polypeptides can show, e.g., increased / decreased activity or increased / decreased stability.
You'll also be interested in:
Examples of using Polypeptides
Show more
The toxicity of these polypeptides is well known
These polypeptides can be prepared by known methods
Pepsin breaks down proteins into polypeptides
Examples of using Modified
Show more
A modified sine wave is generated by this conversion
This warranty may be modified only by RedMax
This modified virus seems to really work
