Examples of 'murine antibodies' in a sentence
Meaning of "murine antibodies"
murine antibodies: This phrase describes antibodies derived from or produced in mice (murine species) for research, diagnostic, or therapeutic purposes. It is commonly used in scientific, medical, or pharmaceutical fields to specify the origin or source of antibodies used in experiments, tests, or treatments targeting specific antigens or pathogens
How to use "murine antibodies" in a sentence
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murine antibodies
Murine antibodies of the same isotype were employed as controls.
The hypervariable region sequences of the original murine antibodies are boxed.
Murine antibodies are highly antigenic in humans.
Alanine is commonly found at this position in both human and murine antibodies.
Murine antibodies in vitro are thereby transformed into fully human antibodies.
Chimeric antibodies which are largely human in composition are substantially less immunogenic than murine antibodies.
Murine antibodies secreted by hybridoma cell lines can also be used.
Binding of biotinylated antibody decreases with increasing amounts of chimeric and control murine antibodies.
The administration of murine antibodies to human subject is associated with many drawbacks.
It should be noted that both Bexxar and Zevalin are based on murine antibodies.
Murine antibodies have the potential to generate an unwanted immunogenic response in patients.
Of these, four are marketed as murine antibodies.
Murine antibodies have characteristics which may severely limit their use in human therapy.
Preferred non-human antibodies are rodent or murine antibodies.
Same of said murine antibodies have a limited neutralizing activity against Factor IX.
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However, for diagnostic uses and research in general murine antibodies are preferred as well.
The murine antibodies were generated according to the following method,.
These families reveal a novel method for the " humanization " or reshaping of murine antibodies.
As noted, murine antibodies play an important role in these technologies.
This limitation has been overcome with the development of a process called " humanization " of murine antibodies.
As noted, murine antibodies play an important role in antibody technology.
The nonhuman, synthetic portions of a humanized antibody often come from CDRs in murine antibodies.
For example, once murine antibodies are obtained, variable regions can be sequenced.
Humanized antibodies, are human immunoglobulins grafted with the CDR regions of the specific murine antibodies.
Once the murine antibodies are obtained, the variable regions can be sequenced.
The initial screen yielded sixty-three murine antibodies that associated with human SEZ6.
Mature murine antibodies with similar, but not identical, sequence can be found.
Alternatively, the anti-FcRn antibodies can be murine antibodies.
Because repeated administration of murine antibodies is required, such administration can cause systemic inflammatory effects.
This was followed by a 2 minute injection of huOX40 and then the murine antibodies.
For antibodies, this step may concern murine antibodies which can not be directly used with humans.
Other murine antibodies that recognize VEGF and inhibit VEGF-induced functions have been reported.
In this example, all of the anti-bacteria binding agents are murine antibodies.
Although chimerization of some murine antibodies resulted in reduced HAMA response, others remained immunogenic.
Figure 53 shows anti-cMet direct binding activities of detected purified murine antibodies.
Humanization of murine antibodies This example sets out a procedure for humanization of a murine anti-PRLR antibody.
Figure 54 shows the HGF-cMet binding competition activities of purified murine antibodies.
Hypervariable regions from the murine antibodies were engineered into VLK2 and VHL acceptor frameworks.
CDina26 comprises a mixture of murine antibodies.
As noted, murine antibodies can be used.
Fig . 7 ELISA analysis of blood samples for the presence of murine antibodies.
Non-human, such as murine antibodies can be humanized.
Fig . 23 shows results of an ELISA assay measuring C1q binding by the indicated murine antibodies.
The human and murine antibodies were specific for human ApoA-I, and demonstrated minimal cross-activity.
Radioimmunotherapy ( RIT ) involves the use of radioactively-conjugated murine antibodies against cellular antigens.
Half-lives for murine antibodies are in the range of 12 to 48 hours in humans.
As used herein, the term " antibody " encompasses chimeric, humanized, human and murine antibodies.
MsIgG1 and MsIgG2a are murine antibodies against irrelevant antigens.
Bound murine antibodies were detected by goat anti-mouse IgG - ( Fc-specific ) - HRP as a tracer.
The same observation, however, was not made for murine antibodies to murine 7E3 Fab.
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Murine cells are no smaller than human cells
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