Examples of 'murine antibody' in a sentence
Meaning of "murine antibody"
murine antibody - This phrase describes an antibody derived from mice, often used in research and medical applications
How to use "murine antibody" in a sentence
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murine antibody
An antibody of the invention is not a murine antibody.
The murine antibody genes were cloned from hybridomas.
The antigen binding protein is not a murine antibody.
A murine antibody may be altered to appear antigenically more human.
An antigen binding protein of the invention is not a murine antibody.
The high dose murine antibody therapy is well tolerated in patients.
These data indicated that the humanized antibody binds with similar affinity as the murine antibody.
The present inventors have identified a murine antibody as described in the examples.
The murine antibody may be a neutralizing antibody against RSV.
A standard ELISA assay was performed for detection of murine antibody.
Preferably the murine antibody is a neutralizing antibody against RSV.
For example, the first specific binding agent can be a murine antibody.
It is also preferable that said murine antibody is an antibody against RSV F antigen.
The murine antibody may be a neutralizing antibody against RSV F antigen.
Generally, no binding is detectable in the channel injected with non-specific murine antibody.
See also
In one instance, the antigen binding domain is a murine antibody or antibody fragment described herein.
A reagent according to claim 2, wherein the first specific binding agent is a murine antibody.
Again though, because the murine antibody is a foreign protein, there is the potential for immunogenicity.
For example, an antibody used in murine animal experiments is ideally a fully murine antibody.
The monoclonal murine antibody defined in a has been designated MFP5.
Preferably, the humanized antibody specifically binds to the same epitope as the donor murine antibody.
The six CDRs in the murine antibody are mounted structurally on a V region " framework " region.
Summary of the sequences of the murine antibody ABTIM3.
From a murine antibody that specifically binds HMW-MAA.
The blocking P-selectin antibody of the preceding claims that is a murine antibody.
For control experiments, the nonspecific murine antibody preparation described in Example 8 was used.
Preferred binding molecules of the invention are less immunogenic than the starting 6C8 murine antibody.
OX7 is a murine antibody that recognises the murine AKR lymphoma.
Preferably, the non-human antibody is a murine antibody.
Preferably, the murine antibody is neutralizing antibody against RSV F antigen.
Natalizumab is a humanized version of an alpha4-specific murine antibody.
In one embodiment, a murine antibody which binds human a4B7 can be used.
This level of response was exceeded by 9 of the 12 animals given the murine antibody.
The anti-HER2 murine antibody was conjugated to the drug using a cleavable pH-sensitive spacer.
For example, chimaeric antibodies may include human and murine antibody domains, e . g.
Furthermore, OKT10 is a murine antibody rendering it unsuitable for human administration.
Interestingly, a homologous amino acid, threonine, is found at this position in the murine antibody.
The parental murine antibody 8 shows a low VF value and a negative AS ∘ ‡ ass.
The compositions according to claim 3, wherein the anti-IgE antibody is a humanized murine antibody.
Mc3 is a murine antibody that reacts with the human milk fat globule antigen BA46.
Using FR shuffling, Dall'Acqua and co-workers humanized a murine antibody.
The present invention provides the anti-CD37 murine antibody HH1 as carrier for radioisotope.
In yet another embodiment, a VLA-4 binding antibody may be a humanized version of a murine antibody.
The murine antibody that has been humanized will be called antibody 13C3 throughout the present application.
Figure 2A summarizes affinity data for the murine antibody ABTIM3 and another TIM-3 binding antibody.
A murine antibody isotyping kit was purchased from Boehringer Mannheim ( Indianapolis, IN ).
This chimeric antibody is derived from the murine antibody c4C13.
The known murine antibody 2B7 is inactive in this assay up to a concentration of 83nM.
In both figures, an " m " prefix connotes a murine antibody and an " h " connotes a humanized antibody.
The method of claim 1 or 2, wherein said first anti-U-TAA antibody is a murine antibody.
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The kinetics of antibody decline are also similar
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Examples of using Murine
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Murine cells are no smaller than human cells
Quantitative analysis of murine reproductive tract infection
Murine monoclonal antibodies are fully mouse derived
