Examples of 'nalmefene' in a sentence
Meaning of "nalmefene"
nalmefene (noun) - A drug used to reduce alcohol consumption in people with alcohol dependence or addiction
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- An opiate derivative used mainly to manage alcoholism.
How to use "nalmefene" in a sentence
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nalmefene
It is unknown whether nalmefene is excreted in human milk.
Selincro contains the active substance nalmefene.
Iii precipitating nalmefene as a pharmaceutically acceptable salt.
Iv optionally purifying the obtained nalmefene salt.
Are using naltrexone or nalmefene to treat alcohol or opioid dependence.
Nalmefene hydrochloride is considered to be an opioid derivative.
A more preferable example is nalmefene hydrochloride dihydrate.
Nalmefene also appears effective and works in a similar manner.
In a particular embodiment nalmefene is in the form of the hydrochloride.
Nalmefene for reduction of alcohol consumption in specific target populations.
Process for recovery of nalmefene hydrochloride.
Thus the nalmefene potentiates the analgesic effect of buprenorphine.
Selincro is medicine that contains the active substance nalmefene.
The lactate salt of the nalmefene is provided as reference example.
Nalmefene is an opiate derivative structurally related to the opiate antagonist naltrexone.
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The only known salt of nalmefene is the hydrochloride salt.
All solubilities are normalised to the relative solubility of nalmefene free base.
If you are allergic to nalmefene or any of the other ingredients of this medicine.
The compound forms were buprenorphine HCl and nalmefene HCl dihydrate.
Nalmefene is similar to naltrexone and is used for the same purposes as naltrexone.
A process for the manufacturing of nalmefene comprising the steps.
Nalmefene is an opiate derivative quite similar in structure to the opiate antagonist naltrexone.
Studies in rats have shown excretion of nalmefene or its metabolites in milk.
Nalmefene has primarily been developed for use in the management of alcohol dependence.
If you are taking naltrexone or nalmefene for the treatment of alcohol or opioid dependence.
Nalmefene hydrochloride obtained by the present method may be used in a pharmaceutical composition.
There seems to be a small impairment in cognitive and psychomotor performance after administration of nalmefene.
Said nalmefene hydrochloride dihydrate or monohydrate may be used in the preparation of pharmaceutical compositions.
An assay for both fentanyl free base and nalmefene HCl was performed using liquid chromatography.
Nalmefene salts as medicaments for reducing alcohol consumption or for preventing excessive alcohol consumption.
The seed did not dissolve and Nalmefene started to crystallize.
Naltrexone and nalmefene are opioid antagonists that can block the pharmacological effects of buprenorphine.
Ii further processing of naltrexone obtained from i to nalmefene optionally by the Wittig reaction.
Preferably Nalmefene HCl dihydrate is used as seeding material.
A further aspect of the present invention relates to methods for obtaining Nalmefene hydrochloride dihydrate.
The study concluded that nalmefene appears to be effective and safe in reducing heavy drinking.
Especially preferred antagonists comprise naltrexone, nalmefene and naloxone.
In one embodiment Nalmefene hydrochloride as monohydrate is used.
The use according to claim 1 wherein the antagonist is nalmefene or naltrexone.
Nalmefene can be produced from naltrexone by the Wittig reaction.
The present invention relates to Nalmefene hydrochloride dihydrate represented by the below formula.
Nalmefene hydrochloride is also to be exempted from the Schedule to the Narcotic Control Regulations.
Recovery of Nalmefene hydrochloride.
Nalmefene hydrochloride is also recommended for exemption from the Schedule to the Narcotic Control Regulations.
In addition, injectable nalmefene is no longer available on the market.
Nalmefene is an opioid system modulator with a distinct μ, δ, and κ receptor profile.
In a more particular embodiment, nalmefene is in the form of the hydrochloride dihydrate.
Nalmefene is an opioid system modulator with a distinct µ, δ and k receptor profile.
For comparison, the solvate formation from nalmefene hydrochloride was also investigated.
Both nalmefene and naltrexone are potent µ-opioid antagonists.
