Examples of 'nucleoside analogs' in a sentence
Meaning of "nucleoside analogs"
nucleoside analogs: These are chemical compounds that have a similar structure to nucleosides, which are the building blocks of DNA and RNA. Nucleoside analogs are often used in medicine as antiviral or anticancer agents, as they can interfere with the replication of viruses or cancer cells
How to use "nucleoside analogs" in a sentence
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nucleoside analogs
Their mode of action is similar to nucleoside analogs.
Two nucleoside analogs alone.
This invention relates to dideoxy nucleoside analogs.
A number of phosphonate nucleoside analogs have been described in the literature.
Antiviral combinations containing nucleoside analogs.
The objective of synthesizing nucleoside analogs from methyl furanoside was unsuccessful.
The present invention relates to the field of nucleoside analogs.
The relative phosphorylation of the nucleoside analogs is correlated to deoxythymidine phosphorylation.
Nucleoside analogs are commonly used in treatment of virus infections and cancer.
This can be achieved using nucleoside analogs such as EdU.
Nucleoside analogs such as didanosine undergo intracellular conversion to active triphosphate metabolite.
This invention relates to certain carbocyclic nucleoside analogs which are useful as immunosuppressants.
The antiviral nucleoside analog can be selected from known nucleoside analogs.
The synthesis of a variety of nucleoside analogs involving modifications in the carbohydrate ring is described.
Among the antiviral agents currently under study which seem to possess selectivity are nucleoside analogs.
See also
It was also determined how efficiently the nucleoside analogs competed with deoxythymidine phosphorylation.
Some nucleoside analogs may be efficacious because of their ability to inhibit adenosine kinase.
After incorporation into nucleic acids the nucleoside analogs terminate the chain elongation process.
Nucleoside analogs are a class of antiviral drugs that work by inhibiting viral nucleic acid synthesis.
The most commonly used combinations include two nucleoside analogs with or without a protease inhibitor.
Nucleoside analogs have been used clinically for the treatment of viral infections and cancer.
The EL mass spectra of the nucleoside analogs are discussed.
Nucleoside analogs have also been developed for the treatment of Flaviviridae infections.
Field of the Invention The present invention relates to the field of nucleoside analogs.
Thymidine kinase converts nucleoside analogs or prodrugs into potent cytotoxic agents in dividing cells.
In addition, an siRNA may be modified or include nucleoside analogs.
The most commonly used purine nucleoside analogs for WM have been fludarabine and cladribine.
The company 's research and development concentrated on nucleoside analogs.
The first RT inhibitors were nucleoside analogs such as AZT and ddI.
Most nucleoside analogs are classified as anti-metabolites.
As described above, host cells phosphorylate nucleoside analogs to nucleotide analogs.
In a few cases, nucleoside analogs exert effects at lower phosphate levels.
In general, these compounds are structural analogs of the monophosphates nucleoside analogs.
As a result, several nucleoside analogs have been developed as antiviral agents.
However, the viruses may not be eliminated altogether by nucleoside analogs alone.
One of the most successful nucleoside analogs developed as an antiviral agent to-date is acyclovir.
Figures 7 and 8 show the synthesis of intermediates useful for synthesis of carbocyclic nucleoside analogs.
Some nucleoside analogs are considered to have structural similarities to particular naturally-occurring nucleosides.
The enzyme also efficiently phosphorylates several anti-viral and anti-cancer nucleoside analogs.
For example, nucleoside analogs have been used in the treatment of cancers and viral infections.
A still further example is the use of C nucleoside analogs as 3 ' terminal residues.
The uracil nucleoside analogs have been evaluated also for their anti-HIV and antitumor activities.
The OAT1 transporter transports a number of nucleoside analogs central to antiviral therapy.
Currently, nucleoside analogs are clearly the preferred therapeutic agents for HSV infections.
The antiviral drugs AZT and d4T are nucleoside analogs associated with thymine.
Nucleoside analogs such as tiazofurin, ribavirin and mizoribine also inhibit IMPDH I.
Examples of these are anti-viral nucleoside analogs that must be phosphorylated and the lipid-lowering statins.
Keywords, photochemistry of cyclobutanones, oxacarbene, nucleoside analogs.
Table 2, Phosphorylation of nucleoside analogs by the multisubstrate deoxynucleoside kinase.
Nucleoside reverse transcriptase ( RT ) inhibitors - also called nucleoside analogs.
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