Examples of 'nucleotide analogs' in a sentence
Meaning of "nucleotide analogs"
Nucleotide analogs are chemical compounds that resemble nucleotides (the building blocks of DNA and RNA) but have been modified to serve specific purposes in biochemistry, molecular biology, or pharmaceutical research
How to use "nucleotide analogs" in a sentence
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nucleotide analogs
Many antiviral drugs are nucleoside or nucleotide analogs.
Nucleotide analogs are well known to those of skill in the art.
Substrate molecules may also contain nucleotide analogs.
The nucleotide analogs are not limited to a specific sugar moiety.
Is a substituent found in prior art phosphonomethoxy nucleotide analogs.
Nucleotide analogs for sequencing.
The term nucleotide also encompasses nucleotide analogs.
The nucleotide analogs are not limited to a specific phosphate group.
Conjugates can be chemically linked to the nucleotide or nucleotide analogs.
Nucleotide analogs can also be modified at the phosphate moiety.
Primers optionally may include modified nucleotides or nucleotide analogs.
Nucleotide analogs can also include modifications of the sugar moiety.
A variety of different label moieties are readily employed in nucleotide analogs.
Dozens of other nucleotide analogs have also been tested in antisense technology.
The primer can be added before or during the providing of nucleotide analogs.
See also
The synthesis of a number of phosphonate nucleotide analogs have been described in the literature.
A nucleic acid sample may be sequenced using tagged nucleotides or nucleotide analogs.
Nucleotide analogs may also comprise modifications to the sugar portion of the nucleotides.
The present invention concerns nucleotide analogs and their compositions and use.
Nucleotide analogs can also be modified to achieve any of the improved properties desired.
The housing is constructed to facilitate identification of labeled nucleotide analogs positioned on the support.
Many nucleotide analogs are available and can be incorporated by the polymerases of the invention.
This will allow the selective delivery of antiviral nucleotide analogs into hepatic cells.
Nucleotide analogs include base analogs and comprise modified forms of deoxyribonucleotides as well as ribonucleotides.
The coumarin moiety is used to track purification of intermediates and the final nucleotide analogs.
This preferably takes place before additional nucleotide analogs are incorporated into the oligonucleotide primer.
Nucleotides which confer nuclease resistance used in accordance with the invention are preferably nucleotide analogs.
Nucleotide analogs Provided herein are analogs of nucleotides.
Phosphodiester bonds or phosphothioate bonds may link the nucleotides or nucleotide analogs of the linkers.
Nucleotide analogs are well-known in the art.
A DNA or RNA analog can be synthesized from nucleotide analogs.
In some embodiments, nucleotide analogs can reduce hybridization specificity.
Methods for preparing anti-viral nucleotide analogs.
Nucleotide analogs ( as described below ) can be derivatized similarly to nucleotides.
The preparation of the nucleotide analogs was as follows,.
Nucleotide analogs may be selected from sugar - or backbone-modified ribonucleotides.
As described above, host cells phosphorylate nucleoside analogs to nucleotide analogs.
In some embodiments, nucleotide analogs can stabilize hybrid formation.
As mentioned above, the capture probes may be polymers of synthetic nucleotide analogs.
In some embodiments, nucleotide analogs can destabilize hybrid formation.
Polynucleotides can include nonstandard nucleotides, such as nucleotide analogs or modified nucleotides.
In some embodiments, nucleotide analogs can enhance hybridization specificity.
A polynucleotide may comprise modified nucleotides, such as methylated nucleotides and nucleotide analogs.
Conversely, the nucleotide analogs of the invention avoid these two pitfalls.
Further, the primer and / or template can include one or more nucleotide analogs.
Moreover, the base of the nucleotide analogs is not limited to a specific base.
The oligonucleotides of the present invention can include non-natural nucleotide analogs.
Representative examples of nucleotide analogs can be selected from sugar - or backbone-modified ribonucleotides.
In some embodiments, a polymerase is modified to enhance incorporation of the nucleotide analogs disclosed herein.
Thus, nucleotide analogs can have altered sugar moieties or inter-sugar linkages.
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