Examples of 'nucleotide substitutions' in a sentence

Meaning of "nucleotide substitutions"

Nucleotide substitutions: In the field of genetics, a nucleotide substitution refers to the replacement of one nucleotide base with another in the DNA sequence, which can lead to genetic variations and mutations

How to use "nucleotide substitutions" in a sentence

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nucleotide substitutions
Nucleotide substitutions as part of gene conversion events are excluded.
Most of the mutations which were isolated were nucleotide substitutions.
Nucleotide substitutions may result in conservative amino acid substitutions.
Distance bars indicate the number of nucleotide substitutions per site.
None of the nucleotide substitutions resulted in a change in amino acid sequence.
The resulting vectors were sequenced to confirm the corrected nucleotide substitutions.
The most studied are nucleotide substitutions in coding and regulatory regions.
The method uses mutagenic oligodeoxynucleotide cassettes to generate random nucleotide substitutions.
Single nucleotide substitutions or deletions may cause loss of function in the subunit.
Comparisons of rates of synonymous and nonsynonymous nucleotide substitutions indicate no evidence of selection.
Nucleotide substitutions can result in the gain or loss of specific restriction endonuclease site.
Most of these mutations are single nucleotide substitutions which are introduced in a stepwise manner.
All nucleotide substitutions were made silent so as not to change the RdRP protein sequence.
The oligonucleotide pairs were designed to incorporate nucleotide substitutions encoding the amino acid alterations.
Nucleotide substitutions which differ from the starting population consensus are shown in bold.

See also

Sequence table summarising mutations in VH other than single nucleotide substitutions.
Both nucleotide substitutions and single trinucleotide repeat polymorphisms have been found in this gene.
Distribution of unselected nucleotide substitutions along the Ramos VH.
Nucleotide substitutions can be introduced into DNA segments by methods well known to the art.
This involved the introduction of 5 nucleotide substitutions.
The remaining seven nucleotide substitutions were located in the proximal promoter region and introns.
In this study, the nucleotide changes were all single nucleotide substitutions.
Conservative nucleotide substitutions thus also include silent mutations and differential codon usage.
The closed triangles indicate the positions of nucleotide substitutions in the cDNA insert of pCAM1.
Nucleotide substitutions can be performed, as well as chemical modifications of the probe.
For example, truncated sequences, nucleotide substitutions or other modifications are employed.
Nucleotide substitutions may be performed, as well as chemical modifications of the probe.
For example, truncated sequences, nucleotide substitutions or other modifications may be employed.
The underlined letters indicate the Miu i site created by the 5 nucleotide substitutions.
The deviations are preferably nucleotide substitutions which retain the original length of the spacer sequence.
A 5 ' end phosphorylated oligonucleotide containing 2 nucleotide substitutions was prepared,.
These mutations included nucleotide substitutions ( transitions and transversions ), as well as deletions and insertions.
Those from separate localities differed by from 1 to 7 nucleotide substitutions.
Thus, the simultaneous creation of nucleotide substitutions in adjacent positions is a rare event.
The nucleotide substitutions are underlined in the primers shown in Table 5.
Figure 3 Distribution of unselected nucleotide substitutions along the Ramos VH.
The same nucleotide substitutions indicated in Figure 9 are also underlined and highlighted here.
The scale bar below the dendrogram indicates 1 nucleotide substitutions per 100 nucleotides.
The same nucleotide substitutions indicated in FIG . 9 are also underlined and highlighted here.
The GL2 and GL3 siRNA duplexes differ by only 3 single nucleotide substitutions ( boxed in gray ).
Various nucleotide substitutions in the conserved Stem 1 were prepared and their affinity to HIV-RT determined.
Figure 53 describes nucleotide substitutions used to reduce secondary structure.
The 52 nucleotide substitutions were made to replace T-rich sequences by more GC-rich sequences.
There were only 15 nucleotide substitutions in high passage ISU55 strain.
The number of net nucleotide substitutions between the two populations was 0.0007, indicative of a recent divergence.

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