Examples of 'oligomeric compounds' in a sentence
Meaning of "oligomeric compounds"
oligomeric compounds: Molecules that are made up of a few monomer units, typically between three to ten such units. These compounds are intermediate between monomeric molecules and polymeric structures
How to use "oligomeric compounds" in a sentence
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oligomeric compounds
The present invention provides oligomeric compounds.
Another group of oligomeric compounds includes oligonucleotide mimetics.
There are numerous methods for preparing conjugates of oligomeric compounds.
Treatment with oligomeric compounds.
Oligomeric compounds also include naturally occurring nucleic acids.
Linkage modified gapped oligomeric compounds and uses thereof.
Oligomeric compounds included oligonucleotides.
The present invention provides oligomeric compounds for use in therapy.
The oligomeric compounds according to the invention are potent modulators of the target.
Compositions of the invention can contain two or more oligomeric compounds.
Examples of gapped oligomeric compounds are illustrated in the example section.
The resulting library members can be small organic molecules or oligomeric compounds.
Such modified oligomeric compounds can be described as having a particular motif.
This allows for selective chemistry to arrive at a desired compound or oligomeric compounds.
Either or both of the first and second oligomeric compounds may be oligonucleotides.
See also
Complementary oligomeric compounds need not have nucleobase complementarity at each nucleoside.
Groups can be selectively incorporated into oligomeric compounds of the invention as precursors.
Oligomeric compounds may also contain one or more substituted sugar moieties.
In one embodiment of the invention the oligomeric compounds are suitable antisense drugs.
The gapped oligomeric compounds provided herein have been shown to have improved properties.
Pharmaceutical and other compositions comprising the oligomeric compounds of the invention are also provided.
Oligomeric compounds of the invention may also contain one or more substituted sugar moieties.
The fluorochemical compositions of the invention generally comprise mixtures of alkylated fluorochemical oligomeric compounds.
Such oligomeric compounds will have at least one conjugate attached thereto to modulate their activity.
Oligonucleotide Mimetics Another group of oligomeric compounds includes oligonucleotide mimetics.
Oligomeric Compounds The present invention provides oligomeric compounds.
Certain Modified Nucleosides Provided herein are oligomeric compounds comprising modified nucleosides.
Oligomeric compounds can be linear or circular, and may include branching.
In certain embodiments, oligomeric compounds are single stranded.
In certain embodiments, the present invention provides oligomeric compounds.
Preparation of the oligomeric compounds of formula IV can proceed in similar fashion.
In certain instances, the present disclosure provides oligomeric compounds.
In certain embodiments, oligomeric compounds are antisense compounds.
Oligomeric compounds include oligonucleotides and their analogs, mimics or mimetics.
In certain embodiments, oligomeric compounds are chimeric oligonucleotides.
Isocyanates may be aromatic, cycloaliphatic or aliphatic and may be monomeric or oligomeric compounds.
In certain instances, oligomeric compounds are comprised only of an oligonucleotide.
Hybridization " Hybridization " means the pairing of complementary strands of oligomeric compounds.
In certain embodiments, oligomeric compounds are oligonucleosides.
Oligomeric compounds include oligonucleotides, oligonucleosides, oligonucleotide analogs, modified oligonucleotides and oligonucleotide mimetics.
In certain instances of the disclosure, oligomeric compounds are oligonucleosides.
In certain oligomeric compounds for use in in vivo methods, the cell is in a human.
In certain instances of the disclosure, oligomeric compounds are chimeric oligonucleotides.
Monomeric and oligomeric compounds are preferably selected from the group of diamines, triamines, tetramines.
In certain instances of the disclosure, oligomeric compounds are antisense oligonucleotides.
Oligomeric compounds are also provided having at least one bicyclic nucleoside having formula I, wherein,.
In another embodiment, post-labelling of the oligomeric compounds according to the invention is contemplated.
Alumoxane compounds include, but are not limited to, oligomeric compounds.
In certain embodiments, oligomeric compounds are comprised only of an oligonucleotide.
As used herein, " polymeric moiety " can include oligomeric compounds.
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