Examples of 'p-gp' in a sentence
Meaning of "p-gp"
p-gp (noun): An abbreviation for P-glycoprotein, a protein that plays a role in transporting substances across cell membranes. In English, this term is often used in scientific or medical contexts
How to use "p-gp" in a sentence
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p-gp
P-gp is also found in brain capillary endothelial cells.
Idebenone is not a substrate for p-gp in vitro.
P-gp is likely involved in talazoparib active renal secretion.
Grazoprevir is not a P-gp inhibitor based on in vitro data.
P-gp has wide selection of substrates from many therapeutical groups.
Trametinib is an in vitro substrate of the efflux transporter P-gp.
P-gp is located in the cell membrane and functions as a drug efflux pump.
Fidaxomicin may be a mild to moderate inhibitor of intestinal P-gp.
P-gp administered simultaneously, or in a close time window to the nano lipo formulation.
Ticagrelor as well as the active metabolite are P-gp substrates.
The P-Gp protein displays broad specificity towards several structurally unrelated chemotherapy agents.
Caution required with concomitant use P-gp interactions.
P-gp is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity.
In vitro data show that netupitant is a P-gp inhibitor.
Results in vivo with the P-gp substrate fexofenadine were inconclusive.
See also
Edoxaban is a substrate for the efflux transporter P-gp.
Effect of ticagrelor on other P-gp substrates has not been studied.
The P-gp inhibitors can be given sublingually.
Selexipag is a weak substrate of the P-gp efflux pump.
Strong inhibitors of P-gp may lead to increased talazoparib exposure.
Rucaparib also marginally inhibits P-gp in the gut.
The P-gp inhibitors can be given intranasally.
Vortioxetine is a poor P-gp substrate and inhibitor.
The P-gp inhibitors can be given intrathecally.
Telaprevir effect on P-gp transport in the gut.
The P-gp inhibitors can be given topically.
The mechanism of interaction is P-gp inhibition by atazanavir and cobicistat.
The dihydrodiol metabolite and other metabolites are P-gp substrates.
Efficacy assessments in P-gp expressing xenograft models.
Temsirolimus and sirolimus were demonstrated to be substrates for P-gp in vitro.
The effect of rifaximin on P-gp transporter was not evaluated in vivo.
Tissue distribution of drugs which are transported by P-gp may be increased.
Cariprazine is a P-gp inhibitor in vitro at its theoretical maximum intestinal concentration.
Based on an in vitro study tigecycline is a P-gp substrate.
The use of P-gp inhibitors is known to those skilled in the art.
Canagliflozin has been observed to inhibit P-gp in vitro.
Vesicles containing P-gp will be used for drug transport assays.
Medicinal products transported by P-gp in the intestine.
Preclinical data have demonstrated that trabectedin is a substrate to P-gp.
Empagliflozin does not inhibit P-gp at therapeutic doses.
Eliglustat is a substrate of the efflux transporter P-gp.
Expected due to inhibition of P-gp by daclatasvir.
Dabigatran etexilate is a substrate for the efflux transporter P-gp.
As a result, penetration of parenteral drugs to P-gp expressing tissues will be improved.
Apixaban is not a significant inhibitor of P-gp.
Monitor P-gp substrate concentration for drugs with narrow therapeutic index.
Vemurafenib is a substrate and inhibitor of P-gp in vitro.
In experimental animals, it has been shown that P-gp is a major determinant of aliskiren bioavailability.
Caution should be exercised with concomitant use of P-gp inducers.
In experimental animals, it has been shown that P-gp is a major determinant of Enviage bioavailability.
