Examples of 'peptidomimetic' in a sentence
Meaning of "peptidomimetic"
Peptidomimetic is an adjective used to describe synthetic compounds that mimic the structure and function of peptides
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- A small protein-like chain designed to mimic a peptide, but with altered chemical properties.
How to use "peptidomimetic" in a sentence
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peptidomimetic
Thus a peptidomimetic is an isostere of the corresponding peptide.
These compounds have a peptidomimetic structure.
Peptidomimetic cyclic compounds for treating retinitis pigmentosa.
This analogue may be a peptidomimetic agent.
References to peptidomimetic structures have been provided above.
The ligand can be a peptide or peptidomimetic.
A peptidomimetic can be in the form of an optical isomer or a diastereomer.
The peptide is glucagon or a glucagon analog or a glucagon peptidomimetic.
The term peptidomimetic thus is intended to include isosteres.
This compound may be a peptidomimetic agent.
Cyclic peptidomimetic compounds as immunomodulators.
Chiral intermediates for the preparation of peptidomimetic protease inhibitors.
A peptide or peptidomimetic comprising the amino acid sequence of any of.
It could be either an analog or peptidomimetic.
The development of encoded peptidomimetic libraries for drug discovery.
See also
Also peptidomimetic molecules might be used for this purpose.
In this project we were tested peptidomimetic compounds against both enzymes.
The peptidomimetic macrocycle may be purified after the contacting step.
It will be appreciated that peptidomimetic compounds may also be useful.
Peptidomimetic protease inhibitors.
Peptide and peptidomimetic inhibitors.
Peptidomimetic compounds of formula.
Various methods to effect formation of peptidomimetic macrocycles are known in the art.
The peptidomimetic compound may have enhanced mucosal intestinal permeability.
This protein also facilitates the absorption of numerous peptidomimetic drugs.
Still another class of peptidomimetic derivatives includes phosphonate derivatives.
Also described is the generation of antibodies against the peptidomimetic macrocycles.
The peptide or peptidomimetic can be administered to the cell by any method.
The method may also be applied to synthesize a library of peptidomimetic macrocycles.
Peptidomimetic compounds may be prepared by stereoselective synthetic processes described herein.
The invention also provides methods for selecting peptidomimetic compounds.
The peptidomimetic macrocycle may be refolded after the contacting step.
The spacer of the chimeric polypeptide may comprise a peptidomimetic sequence.
The peptidomimetic precursor may be purified prior to the contacting step.
It therefore offers to effect the synthesis of peptides and peptidomimetic molecules on demand.
Peptidomimetic modelling is implemented by standard procedures known to those skilled in the art.
The invention relates to a method of preparing a sustained release formulation of a peptide or peptidomimetic.
A peptidomimetic generally contains at least one residue that is not naturally synthesised.
A linker may serve to link the polypeptide or peptidomimetic to one detectable moiety.
Or a peptidomimetic thereof.
Further provided are compositions including peptides and peptidomimetic sequences of the invention.
A peptidomimetic is a compound that mimics the conformation and particular features of the peptide.
The compounds of the present invention may be a peptidomimetic which is at least partly unnatural.
The peptidomimetic compounds may be formulated into the compositions as neutral or salt forms.
It is well known that the therapeutic activity of enantiomers of peptidomimetic compounds varies widely.
Peptidomimetic compounds have been designed and synthesized for a number of therapeutically relevant peptides.
The invention further describes the generation of antibodies against the peptidomimetic macrocycles.
Each peptidomimetic may further have one or more unique additional binding elements.
The compound disclosed herein may be a peptidomimetic compound which may be at least partially unnatural.
A peptidomimetic usually does no longer have classical peptide characteristics such as enzymatically scissille peptidic bonds.
