Examples of 'phosphodiesterase activity' in a sentence

Meaning of "phosphodiesterase activity"

phosphodiesterase activity - a biochemical term referring to the activity or function of enzymes that break down phosphodiester bonds in molecules, often used in the context of biological processes and pharmacology

How to use "phosphodiesterase activity" in a sentence

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phosphodiesterase activity
The supernatant was assayed for phosphodiesterase activity.
Variation of phosphodiesterase activity in renal tissue as lupus sets in.
Each fraction was tested for cAMP metabolizing phosphodiesterase activity.
The phosphodiesterase activity of the crude cell extracts was measured.
Additionally we show that striatal neurons display an increased phosphodiesterase activity.
Phosphodiesterase activity was assayed as follows.
The polypeptides can be used to identify compounds that modulate phosphodiesterase activity.
Phosphodiesterase activity assays were performed using cAMP as substrate as follows.
In a preferred embodiment the eucaryotic cell lacks endogenous cyclic nucleotide phosphodiesterase activity.
Assay of phosphodiesterase activity.
A compound for use in such treatment is preferably one that does not have phosphodiesterase activity.
The role of basal phosphodiesterase activity in the regulation of mouse rod photoresponses.
These data show that both sulindac sulfide and exisulind inhibit phosphodiesterase activity.
The essential character of a DNase is phosphodiesterase activity and the ability to hydrolyse DNA.
These compounds elevated cellular cyclic AMP probably by inhibition of phagocyte phosphodiesterase activity.

See also

Finally, no cGMP phosphodiesterase activity was detected in these assays.
CAMP is normally degraded by phosphodiesterase activity.
In addition, the phosphodiesterase activity is not stimulated by the presence of calcium / calmodulin.
The results are expressed as % inhibition of the phosphodiesterase activity.
Phosphodiesterase activity is assayed as described in the protocol of Torphy and Cieslinski, Mol.
The truncated human cGB-PDE polypeptide exhibited phosphodiesterase activity.
Phosphodiesterase activity was measured, as described by Thompson, et al ., Adv.
Calcium / calmodulin was unable to stimulate the measured phosphodiesterase activity in the extract.
Phosphodiesterase activity was determined as described, with minor modifications, in Davis et al ., J. Cyc.
The lysosomal deacylase but not the phosphodiesterase activity was inhibited reversibly by n-butanol.
The method of clause 51, which is an agent that increases phosphodiesterase activity.
The supernatant was assayed for phosphodiesterase activity as in Collicelli et al ., supra.
Preferably, the protein scaffold for this variant have lipase, phosphatase, phytase, or phosphodiesterase activity.
The supernatant was then assayed for phosphodiesterase activity as in Section B, above.
KOR activation by agonists is coupled to the G protein Gi/G0, which subsequently increases phosphodiesterase activity.
The concentration of compound which produces a 50 % inhibition of phosphodiesterase activity ( the IC50 ) is then calculated.
Cells are treated with 0.1 M HCl to stop endogenous phosphodiesterase activity.
The supernatant and the washes showed very little or no phosphodiesterase activity ( data not shown ).
Control extracts ( 10DAB with pADNS ) showed no cAMP phosphodiesterase activity.

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Examples of using Phosphodiesterase
Preferred phosphodiesterase inhibitors include papaverine hydrochloride
This effect is potentiated by several phosphodiesterase inhibitors
It is a major phosphodiesterase in the human cardiac myocyte
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