Examples of 'protein scaffold' in a sentence
Meaning of "protein scaffold"
protein scaffold - A protein scaffold is a structural framework composed of proteins that provides support and organization for various cellular processes
How to use "protein scaffold" in a sentence
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protein scaffold
Another option for a feasible protein scaffold are lipases.
A protein scaffold is comprised of at least two protein scaffold fragments.
The tertiary structure of the protein scaffold can be of any type.
Protein scaffold fragment means a part of the sequence of a protein scaffold.
They consist of a variable peptide loop attached at both ends to a protein scaffold.
A particularly suited protein scaffold for this variant is a glycosylase or is derived from a glycosylase.
The man skilled in the art knows how to select the protein scaffold.
The Affimer protein scaffold is derived from the cysteine protease inhibitor family of cystatins.
They usually comprise of a variable peptide loop attached at both ends to a protein scaffold.
In a preferred variant of this aspect, a protein scaffold with hydrolase activity is used.
The biodegradable composite was created by fusing silk protein microfibers to a silk protein scaffold.
Thus, a protein scaffold modified by the covalent attachment of polylysine is encompassed by the invention.
Peptide aptamers consist of a variable peptide loop attached at both ends to a protein scaffold.
Epitope-binding domains can be linked to the protein scaffold at one or more positions.
Polypeptide aptamers may include a short variable peptide domain attached at both ends to a protein scaffold.
See also
In principle, the protein scaffold can have a variety of primary, secondary and tertiary structures.
Alternatively, antibody fragments may be fused to a protein scaffold.
The antibody variant may comprise a protein scaffold comprising CDRs, an antibody mimetic, or a DARPin.
In some embodiments, the targeting moiety may be a protein scaffold.
Bulk proteins useful in formulating protein scaffold compositions include albumin, protamine, or the like.
However, up to six and more SDRs can be inserted into a protein scaffold.
The protein scaffold molecules of the present invention fold into an alpha-helical coiled coil structure.
Preferably the binding agent is an antibody, aptamer, or based on an engineered protein scaffold.
A particularly suited protein scaffold for this variant is a DNA ligase, or is a derivative thereof.
Preferably, pepsin or endothiopepsin or a derivative or homologue thereof is used as the protein scaffold.
Connecting said protein scaffold fragment vÃa a peptide linkage with a first SDR, and optionally.
A peptide aptamer consists of a short variable peptide domain, attached at both ends to a protein scaffold.
Any enzyme can serve as the protein scaffold in step ( a ).
Peptide aptamers consist of a short variable peptide domain, attached at both ends to a protein scaffold.
Alternatively, the protein scaffold may have ligase, lyase, oxidoreductase, or isomerase activity.
Preferably, such defined specificity of the engineered enzymes is not conferred by the protein scaffold.
Preferably, the protein scaffold for this variant have lipase, phosphatase, phytase, or phosphodiesterase activity.
In some embodiments, the A component comprises a protein scaffold.
Such protein scaffold is compatible is angiogenesis process Callegari, A. ; et al.
In some embodiments, A may be a protein scaffold.
As above mentioned, such protein scaffold can comprise from 1 to 6 CDR ( s ) from the original antibody.
In some examples, B1 may be a protein scaffold.
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