Examples of 'quinazoline derivative' in a sentence
Meaning of "quinazoline derivative"
quinazoline derivative: this phrase refers to a chemical compound that is derived from quinazoline, a heterocyclic organic compound with various applications in medicinal chemistry and related fields
How to use "quinazoline derivative" in a sentence
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quinazoline derivative
Trimetrexate is a quinazoline derivative.
A quinazoline derivative as claimed in any one of the preceding claims wherein Z is NH.
Alfuzosine is a quinazoline derivative.
A quinazoline derivative of the formula I.
A preferred cleavage reaction is the treatment of a quinazoline derivative of the formula I with pyridine hydrochloride.
A quinazoline derivative of the following listing,.
A process for the preparation of a quinazoline derivative of formula I.
A quinazoline derivative as claimed in any one of claims 1 to 9 for use as a medicament.
A further particular compound of the invention is a quinazoline derivative of the Formula I wherein.
As stated above a quinazoline derivative of the present invention possesses anti-tumour activity.
In certain embodiments, an a blocker may comprise a quinazoline derivative.
In particular, the invention relates to a quinazoline derivative which exhibits protein tyrosine kinase inhibition.
The quinazoline derivative of formula I is unsubstituted at the 2-position on the quinazoline ring.
Another embodiment of the present invention is a quinazoline derivative of the formula I wherein,.
A quinazoline derivative of the Formula II wherein,.
See also
A particular example of a quinazoline derivative of the Formula ID is,.
A quinazoline derivative of the formula I as claimed in claim 1 selected from.
The hydrochloride salt of the quinazoline derivative of the formula I as claimed in claim 10.
The method of claim 1, comprising administering a pharmaceutical composition comprising the quinazoline derivative of formula ( I ).
Another embodiment is a quinazoline derivative of the formula I of the formula Id, wherein,.
Finally, dehydration and aromatization from E produce quinazoline derivative 2.
Alternatively this group of quinazoline derivatives comprises a quinazoline derivative of the formula I wherein R ¹ is methyl ;.
An embodiment of the present invention is a quinazoline derivative of the Formula I wherein,.
A quinazoline derivative as claimed in claim 1 selected from,.
A preferred compound of the invention is a quinazoline derivative of the Formula I wherein,.
A quinazoline derivative selected from,.
A further embodiment of the invention is a quinazoline derivative of the Formula I wherein,.
A quinazoline derivative as claimed in claim 1 of the formula II, wherein,.
A particular compound of the invention is a quinazoline derivative of the Formula I wherein, -.
A quinazoline derivative as claimed in claim 1 wherein R1 is methoxy.
A further preferred compound of the invention comprises a quinazoline derivative of the formula I wherein R ¹ is methyl ;.
A quinazoline derivative of the formula I as claimed in claim 1,.
A further particular compound of the invention comprises a quinazoline derivative of the formula I wherein R ¹ is methyl ;.
A quinazoline derivative of the formula I, wherein,.
A particular compound of the invention is, for example, a quinazoline derivative of the formula I selected from,.
A quinazoline derivative as claimed in any one of claims 2 to 4 wherein Z is NH.
A preferred compound of the invention is, for example, a quinazoline derivative of the Formula I selected from,.
A quinazoline derivative as claimed in claim 1 or claim 2 wherein R2 is hydrogen.
Another embodiment is a quinazoline derivative of the formula I wherein, p is 1 ;.
The quinazoline derivative of the formula I as claimed in claim 2 being, -.
A quinazoline derivative of the Formula II according to claim 1 wherein,.
A quinazoline derivative as claimed in claim 18 wherein R1 represents methoxy.
A quinazoline derivative of the Formula I according to claim 1 selected from, -.
A quinazoline derivative as claimed in claim 1 or claim 2 wherein R1 represents methoxy.
A quinazoline derivative of the Formula II according to claim 1 selected from, -.
A quinazoline derivative of the formula I as claimed in claim 1 wherein X1 is a direct link ;.
A quinazoline derivative of the formula I as claimed in claim 1 wherein R ¹ is methoxy or ethoxy ;.
A quinazoline derivative as claimed in any one of the preceding claims wherein X1 represents - O -.
A quinazoline derivative of the Formula I according to claim 1 wherein,.
A quinazoline derivative of the formula I wherein X1 is a direct link ;.
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