Examples of 'quinazoline derivatives' in a sentence
Meaning of "quinazoline derivatives"
quinazoline derivatives: Chemical compounds that are derived from quinazoline, often used in pharmaceutical research and drug development
How to use "quinazoline derivatives" in a sentence
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quinazoline derivatives
Quinazoline derivatives and therapeutic use thereof.
The compounds of the invention are quinazoline derivatives.
Use of quinazoline derivatives for neurodegenerative diseases.
Part one aims to develop methods for the preparation of quinazoline derivatives.
Quinazoline derivatives useful as insecticides.
The examples of preferred quinoline or quinazoline derivatives of the present invention are as follows.
Quinazoline derivatives have been proposed for inhibiting protein kinase activity.
A particular value for Z in the quinazoline derivatives of the Formula La is hydroxy.
Quinazoline derivatives as a multiplex inhibitor and method for the preparation thereof.
Heterocyclic substituted 2-amino quinazoline derivatives for the treatment of viral infections.
Quinazoline derivatives for the treatment of viral infections and further diseases.
In particular, the invention relates to quinazoline derivatives which exhibit protein tyrosine kinase inhibition.
Quinazoline derivatives useful for the treatment of peripheral arterial disease and as phosphodiesterase inhibitors.
We have now found that surprisingly certain quinazoline derivatives possess potent anti-tumour activity.
Certain quinazoline derivatives are known to be inhibitors of protein tyrosine kinases.
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A chemical structure-activity relationship determining the anti cancer activity of quinazoline derivatives has not been established.
Novel quinazoline derivatives and their use in perfume compositions.
An example of the synthesis of substituted quinazoline derivatives is shown in Scheme 2.
Quinazoline derivatives for inhibiting cancer cell growth and method for the preparation thereof.
Abstract, This work concerns the design of aminoacridine and quinazoline derivatives.
Quinoline and quinazoline derivatives for the treatment of tumors.
Particular novel compounds of the invention are, for example, quinazoline derivatives of the formula I wherein, -.
Quinazoline derivatives of the Formula VIII may be obtained by conventional procedures.
We have now found that - surprisingly certain 5-substituted quinazoline derivatives possess potent anti-tumour activity.
Quinazoline derivatives and their use as anti-cancer agents.
None of the foregoing patents describes quinazoline derivatives which specifically inhibit p38-a or TGF-B.
The quinazoline derivatives do not contain a substituent at the 5-position on the quinazoline ring.
The invention relates to quinazoline derivatives of the formula I, - wherein,.
Quinazoline derivatives have also been disclosed for use in the inhibition of Aurora-A kinase.
The required quinoline, [ 1,5 ] - naphthyridine and quinazoline derivatives of formula ( VI ) are prepared following literature procedures.
The quinazoline derivatives used herein all strongly inhibited human chymase at concentrations of 100 µM.
We have now found that the quinazoline derivatives of the present invention possess CB3717-type activity.
Quinazoline derivatives or salts thereof according to Claim 1, in which said derivatives are,.
Alternatively this group of quinazoline derivatives comprises a quinazoline derivative of the formula I wherein R ¹ is methyl ;.
Quinazoline derivatives or salts thereof according to Claim 1 or 2, in which n is 1.
For example, certain quinazoline derivatives have been reported recently as inhibitors of p38 kinase.
The quinazoline derivatives of formula ( I ) and pharmaceutically acceptable salts thereof are prepared in Examples 18-61.
However, none of these quinazoline derivatives contain a substituent at the 5-position on the quinazoline ring.
Non-limiting examples of quinazoline derivatives include alfuzosin, bunazosin, doxazosin, prazosin, terazosin and trimazosin.
Quinoline or quinazoline derivatives useful in the treatment of osteoporosis are also disclosed in EP 634169.
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