Examples of 'reovirus' in a sentence
Meaning of "reovirus"
Reovirus is a noun that refers to a type of virus belonging to the Reoviridae family, known for its double-stranded RNA genome
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- Any of a group of RNA viruses, of the family Reoviridae, that infect animals and some plants
How to use "reovirus" in a sentence
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reovirus
Preferably the reovirus is administered in multiple doses.
Targeted administration may be used to administer a reovirus.
The reovirus may be naturally occurring or modified.
The lyophilized formulations optionally include a reovirus.
Kits comprising a reovirus and are also provided.
Reovirus therapy is an example of virus therapy.
A method of making a reovirus having increased infectivity is provided.
Reovirus proteins are indicated on the right.
We therefore developed a simplified method to extract the reovirus.
The reovirus may also be administered systemically.
Immunoinhibition in a mammal renders the reovirus more effective.
Resistance to reovirus infections in chickens is directly related to age.
The immunosuppression results in more effective reovirus treatment.
The reovirus may be a mammalian reovirus or an avian reovirus.
Further described herein are methods of preserving or stabilizing a reovirus.
See also
The reovirus may be a recombinant reovirus.
The disclosure provides for methods of making an improved reovirus.
Reovirus does not replicate in normal cells.
Method of producing infectious reovirus.
The reovirus useful in this invention may be any reovirus.
The invention involves at least a reovirus as the oncolytic virus.
The reovirus can be administered in a single dose or in multiple doses.
These excipients can contribute to the stability of the reovirus.
Any mammalian reovirus can be produced using this method.
Core structure of a reovirus.
Reovirus and adenovirus was isolated from the other samples.
The result indicates that reovirus has replicated in the sample.
The reovirus may be administered by injection into or near a solid neoplasm.
In one embodiment a course of reovirus therapy is administered one or more times.
Reovirus was chromatography at different pH.
Provided herein is a lyophilized formulation in which the reovirus is a mammalian reovirus.
The mammalian reovirus preferentially replicates and kills cancer cells.
The modifications described herein represent an adaptation by the reovirus to human cells.
The inactivated reovirus was used to prepare different inactivated reovirus vaccines.
These cells were also tested for their ability to support reovirus production.
The reovirus is administered in a manner so that it contacts the target neoplastic cells.
The mammal should be rendered immunoinhibited prior to or concurrent with reovirus administration.
The reovirus may also be selected or mutagenized for enhanced oncolytic activity.
A plasmid encoding this ribozyme is introduced in cells that are susceptible to reovirus infection.
A mutant reovirus as described herein can include one or more further mutations.
Three distinct but related types of reovirus have been recovered from many species.
Reovirus particles are obtained using any number of methods known in the art.
We also present evidence that reovirus is useful as an oncolytic agent against mammary tumors.
This disclosure describes modifications in the nucleotide and amino acid sequence of a reovirus.
Methods for preventing reovirus recognition for the treatment of cellular proliferative disorders.
The modifying step can include culturing the reovirus in a human cell line.
Other mammalian reovirus can be produced efficiently by the presently claimed method as well.
Inflammatory changes from the upper respiratory tract are more typical for reovirus infection.
The reovirus is preferably administered prior to or concurrently with administration of the chemotherapeutic agent.
Cell lines derived from pancreatic cancer were investigated for their susceptibility to reovirus infection.
