Examples of 'replicons' in a sentence
Meaning of "replicons"
replicons (noun) - In genetics, replicons are units of DNA that are capable of replicating. They play a crucial role in the replication of genetic material
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- plural of replicon
How to use "replicons" in a sentence
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replicons
Replicons established in infected cell lines were sequenced.
Data obtained from transiently transfected replicons.
They are alien replicons from beyond the moon.
Replicons with such capability are herein referred to as vectors.
The positions of replicons are indicated by arrows.
This suggests a common origin for these replicons.
The replicons are indicated by arrow heads.
The replicon constructs can be bicistronic subgenomic replicons.
Said replicons are known in the art.
One exciting new approach to this problem is by using a replicons.
These replicons also contained a firefly luciferase reporter gene.
Preferred foreign genes in these replicons are selectable markers or reporter genes.
Reconstruction of mutant replicons.
Particularly preferred replicons include the vaccine vectors described below.
Vectors are often replicons.
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The replicons of the instant invention lack functional replication protein sequences.
Precursor vectors may be capable of autonomous replication in the plant cell as are replicons.
Vectors therefore preferably contain the replicons and selectable markers described earlier.
Eukaryotic chromosomes have multiple internal origins and thus contain several replicons.
Many other plant viral replicons are described in the patent publications mentioned above.
Other plasmids with similar selectable markers and replicons could also be used.
The use of replicons has been successful but these have only been recently discovered.
It may therefore be advantageous to have such replicons contained in their original host species.
The replicons may also exhibit transient heterologous nucleic acid expression in the target cell.
The compositions and method comprise the use of replicons derived from alphaviruses.
Replicons are typically introduced into a cell in an RNA form.
An additional object of the invention is to provide replicating HCV replicons.
Additional examples of mammalian replicons include those derived from bovine papillomavirus and EpsteinBarr virus.
DNA sequence analysis of this region showed structural features common to bacterial plasmid replicons.
Alphavirus replicons encoding CMV proteins are used to produce VRPs.
A variety of known Streptomyces promoters and replicons are available for such use.
Replicons containing this heterologous DNA are also provided by this invention.
This DNA can be ligated to form circles without replicons and used for transformation.
Alphavirus replicons encoding one or more RSV proteins are used to produce VRPs.
The ssDNA genome of the circoviruses represent the smallest viral DNA replicons known.
VEE replicons have been shown capable of infecting a variety of animal cell types.
Plasmids and phage DNA by their very nature contain replicons facilitating replication in a host cell.
Such alphavirus replicons comprise sequences encoding one or more RSV proteins or fragments thereof.
The assay demonstrated that these compounds exhibited activity against HCV replicons functional in a cell culture.
Such alphavirus replicons comprise sequences encoding at least two CMV proteins or fragments thereof.
Identification of mutations in HCV replicons.
VEE replicons exploit certain properties of the parent Venezuelan equine encephalitis virus.
Plasmid DNA encoding alphavirus replicons served as a template for synthesis of RNA in vitro.
The Sindbis virus and Semliki Forest virus have been used to build recombinant alphavirus replicons.
Plant virus-based replicons are evidently advantageous.
Supernatants of replicon transfected cells inhibited the expression of luciferase coding IVT RNA and replicons.
Virion-packaged replicons were also tested.
Thus, replicons can be created without the production of virions.
For eukaryotic chromosomes, there are multiple replicons per chromosome.
In this case, the replicons cooperate functionally with each other.
