Examples of 'rho kinase' in a sentence
Meaning of "rho kinase"
rho kinase - Rho kinase is a type of enzyme that plays a crucial role in various cellular functions, including cell movement, proliferation, and smooth muscle contraction. It is often studied for its involvement in diseases such as cancer, cardiovascular conditions, and neurological disorders, making it a target for potential therapeutic interventions
How to use "rho kinase" in a sentence
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rho kinase
Therapeutic agent for glaucoma comprising rho kinase inhibitor and prostaglandin.
The Rho kinase was assayed as follows.
This medicine lowers eye pressure by suppressing the rho kinase enzymes responsible for fluid increase.
The human Rho kinase assay was performed as follows.
The ROCK inhibitory substance is a substance capable of inhibiting a signal mediated vía a Rho kinase.
Inhibition of Rho kinase can be assayed as described.
An object of the present invention is to provide compounds having Rho kinase inhibitory activity.
The Rho kinase pathway regulates mouse adult neural precursor cell migration.
The compounds of the present invention have high affinity for Rho kinase.
The dose of the Rho kinase inhibitor varies depending on the drug type.
TECHNICAL FIELD The present invention relates to a novel amide compound having a Rho kinase inhibitory action.
The Rho kinase has been confirmed to be present in corneal epithelial cells Nirmala SundarRaj.
In a preferred embodiment, the kinase inhibited is a rho kinase.
A Rho kinase inhibitor for use in a method of prophylaxis or treatment of corneal endothelial dysfunction.
In some embodiments, the kinase inhibited may be a rho kinase.
See also
Inhibitors of Rho and Rho kinase also prevented these signs of neuropathic pain.
Bi-and polycyclic substituted isoquinoline and isoquinoline derivatives as rho kinase inhibitors.
Further, Rho kinase is also involved in migration of leukocytes.
However, a specific inhibitor of Rho kinase has not been known to date.
Netarsudil, a Rho kinase inhibitor, is believed to reduce IOP by increasing outflow of aqueous humor.
Thus, the labeled compounds thereof are industrially useful as selective ligands of Rho kinase.
However, it is unknown if Rho kinase is present in other ophthalmic tissues.
The active substance in Rhokiinsa, netarsudil, is a Rho kinase inhibitor.
The Rho kinase inhibitors and the B-blockers of the present invention include salts thereof.
Exoenzyme C3 as such works as a rho kinase inhibitor.
The Rho kinase inhibitors may include, for example, fasudil hydrochloride.
Ros scavenger, nrf2 activator, nox1 and rho kinase inhibitor normalized vascular function.
Figure 8, H1 cells were grown in decreasing concentrations of Rho kinase inhibitors.
Actomyosin contraction is regulated by the Rho kinase and the serine / threonine p21 activated kinase pak-1.
Figure 7, H9 cell proliferation on micro-carriers in various concentrations of Rho kinase inhibitors.
The cells received MEF-CM without Rho kinase inhibitor from day3 onward.
For example, H2O2 activates redox-signaling sensitive pathways such as MAPK and Rho kinase.
The culture medium may contain a Rho kinase ( ROCK ) inhibitor.
The compounds of the formula ( I ) and the formula ( II ) have high affinity for Rho kinase.
N - substituted 5-isoquinolylamine derivatives were disclosed as Rho kinase inhibitors in the International.
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Rho factor is an essential transcription protein in prokaryotes
It is represented with the greek letter rho p
Such a rho zeta theta thing
Examples of using Kinase
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Creatine kinase can be checked if myalgias develop
Blood tests show elevated creatine kinase
Elevation of creatine kinase in blood is indicative of myositis
