Examples of 'shrna' in a sentence
Meaning of "shrna"
shrna (noun) - a term that does not have a widely recognized or defined meaning in English
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- small hairpin RNA, or short hairpin RNA
- Alternative form of shRNA
How to use "shrna" in a sentence
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shrna
Using shRNA in gene and cancer therapies.
The RNAi mentioned may be a siRNA or a shRNA.
A mixture of four different shRNA sequences are provided.
The shRNA is preferably administered in a therapeutically effective amount.
Design of comparable shRNA and artificial miRNA hairpins.
This oligonucleotide can be termed a tandem shRNA construct.
The shRNA sequence is under control of this promoter.
The rate of proliferation of control vs shRNA.
The shRNA may further comprise an overhang region.
The kit contains an siRNA or an shRNA expression vector.
The use of shRNA is particularly preferred.
The promoter choice is essential to achieve robust shRNA expression.
The term shRNA is used herein as a type of siRNA.
In an embodiment the inhibitor is an shRNA.
Nonsilencing control shRNA had no effect on cell proliferation.
See also
Comparison of knockdown efficiency of modified and parent shRNA sequences.
Two independent shRNA constructs were chosen for this purpose.
The cells may express an antisense or siRNA or shRNA or protein.
Predicted miRNA and shRNA structures are based on mFOLD analysis.
The effectiveness of attenuation was verified in all shRNA cells lines.
A shRNA consists of short inverted repeats separated by a small loop sequence.
In an instance the inhibitor is a shRNA.
Personalized shRNA libraries.
The shRNA may then be introduced directly into the cell.
Target sequences for all siRNAs and shRNA clones were different.
The therapeutic gene may also be a gene coding for siRNA or shRNA.
Cells stably expressing shRNA were cultured in the presence or absence of selumetinib.
This system constitutes a criterion of selection during the insertion of an shRNA sequence.
Use of a bacterial vector to obtain shRNA expression in cells is a relatively recent approach.
The control used is the pLVTHM plasmid which expresses an ineffective shRNA sequence.
A protein expression construct or a shRNA expression construct into said mammalian cell.
Such agents are referred to herein as RNAi agents and include siRNA and shRNA.
Mapping cleavage sites for corresponding shRNA and artificial miRNA vectors.
Any of the methods using siRNA may also be carried out using shRNA.
Three colonies for each of the six shRNA vectors were picked and expanded.
Processing was generally consistent among cell lines and among different shRNA sequences.
Mature shRNA sequence distributions were calculated for each shRNA before averaging across shRNAs.
We note siRNAs only in mice transgenic for the shRNA expression cassette.
The shRNA molecule contains sense and antisense sequences from a target gene connected by a loop.
Light emitted from mice receiving the renilla shRNA was reduced only slightly.
Quadruplicate cell counts were averaged and normalized relative to that of the control shRNA.
The use of this transcript produces a more physiological shRNA that reduces toxic effects.
Promoters suitable for expressing shRNA are those indicated in the paragraph above for expressing siRNA.
The pharmaceutical compositions of the invention comprise a therapeutically effective amount of the vector encoding shRNA.
ShRNA sequences are named for the targeted exon.
Any of the methods described herein using siRNA may also be carried out using shRNA.
Construction of adenovirus vector expressing shRNA molecule targeting TS.
ShRNA delivered to tumor cells is transferred to the insides of cells vía endocytosis.
DsRNA molecule contains more than three siRNA or shRNA.
Each shRNA sequence is complementary to an unique part of the ATM mRNA sequence.
