Examples of 'single-chain' in a sentence
Meaning of "single-chain"
Single-chain is a noun used in the context of molecular biology or biochemistry to describe a type of molecular structure composed of a single chain of molecules, as opposed to multiple chains. It is often used in discussions about protein structure and function.
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- Having only a single chain of carbon atoms.
How to use "single-chain" in a sentence
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single-chain
A single-chain meganuclease has multiple advantages.
Such an antibody can be in a single-chain or heteromultimeric format.
Single-chain antibodies can also be prepared.
Recovering the single-chain clostridial neurotoxin.
Single-chain coiled coil scaffold constructs.
Sc rtTA is a single-chain version of rtTA.
Single-chain antibodies as antisenilins can also be produced.
In an embodiment the antibody fragment is a single-chain antibody.
Three single-chain antibodies were produced.
Soluble TCRs may be heterodimeric or single-chain molecules.
Recombinant single-chain antibodies have also been described.
As an example a scFv is a single-chain antibody.
Single-chain fusion polypeptides comprising a plurality of additional domains.
Domain structure of the inventive single-chain fusión polypeptide.
Single-chain antibody fragments for transferring substances into cells.
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In an aspect of the invention the single-chain polypeptide is an isolated polypeptide.
The single-chain meganuclease allows the control of the oligomerisation.
A targeting domain such as a single-chain antibody or an antibody fragment domain.
Preferably, the polypeptide of the present invention is a single-chain polypeptide.
The isolated single-chain protein is defined in the claims.
In one embodiment the effector moiety is a single-chain effector moiety.
These single-chain surfactants are found to be very advantageous in aqueous bitumen emulsions.
Molecular modeling of parallel and antiparallel single-chain coiled coils.
The above single-chain antibodies can also comprise derivatives thereof.
In one embodiment, the bispecific antibody is a bispecific single-chain antibody.
A polynucleotide encoding the single-chain polyspecific binding molecule of claim 1.
The antibodies useful in the present invention can be single-chain antibodies.
Construction of single-chain fusión polypeptides comprising one or more additional domains.
The construction of the different bifunctional single-chain constructs is described below.
Neither single-chain meganuclease cleaved the hybrid site to a significant degree.
Methods of intracellular conversion of single-chain proteins into their di-chain form.
For example, single-chain engineered immunoglobulins could be useful in certain immunocompromised patients.
Particularly preferred embodiments of the single-chain hormones of the invention include,.
Single-chain antibodies as antisenilins can also be produced according to the present invention.
In an aspect of the inventive method the single-chain polypeptide is an isolated polypeptide.
The single-chain hormones are also useful as reagents in a manner similar to the heterodimers.
The antibodies useful in the present disclosure can be single-chain antibodies.
Disclosed herein are single-chain framework reagents that have the general structures,.
In preferred embodiments, the nucleases used to practice the invention are single-chain meganucleases.
Single-chain nucleic acids having these two designed sequences are separately synthesized.
In another aspect, disclosed are recombinant single-chain meganucleases resulting from these methods.
The following protocol is used for the construction of each single-chain toxin.
It consists of a single-chain glycoprotein synthesized in the liver, adipose tissue and endothelial cells.
At least one instance of preparing a successful single-chain form of a heterodimer is now known.
In single-chain hoists, a chain shackle is necessary in the hook cylinder of the hoisting hook.
In another embodiment, the antibody of the invention is an antibody fragment or a single-chain antibody.
A similar single-chain protein comprising the heavy chain variable regions is also possible.
Antibodies can also be prepared recombinantly in various forms such as single-chain antibodies.
Once expressed, the single-chain polypeptide may be purified by standard protein purification methods.
Furthermore, humanized monoclonal or phage encoded single-chain monoclonal antibodies may be used.
