Examples of 'single-chain antibody' in a sentence
Meaning of "single-chain antibody"
single-chain antibody: A single-chain antibody is a type of antibody that is engineered by connecting the variable domains of the heavy and light chains of an antibody with a short linker peptide. This results in a single polypeptide chain with antigen-binding capabilities similar to a natural antibody. Single-chain antibodies are used in research, diagnostics, and therapeutics
How to use "single-chain antibody" in a sentence
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single-chain antibody
In an embodiment the antibody fragment is a single-chain antibody.
Single-chain antibody fragments for transferring substances into cells.
As an example a scFv is a single-chain antibody.
Preferably, single-chain antibody is one amino acid chain sequence coded by one nucleotide chain.
In one embodiment, the bispecific antibody is a bispecific single-chain antibody.
A targeting domain such as a single-chain antibody or an antibody fragment domain.
In another embodiment, the antibody of the invention is an antibody fragment or a single-chain antibody.
For example, a single-chain antibody may comprise a tether segment for linking to the encoding polynucleotide.
Therefore, in a particular embodiment the gene of interest encodes a single-chain antibody or a precursor thereof.
A single-chain antibody or antibody fragment, such as a Fab or Fc fragment domain.
Convenient restriction sites have been included for in-frame fusión of single-chain antibody genes.
Advantageous is a single-chain antibody wherein VH is located at the N-terminus of the recombinant antibody.
In another preferred embodiment of the invention, the polypeptide described above is a bispecific single-chain antibody.
Wherein the single-chain antibody has the VH framework and the VI framework of.
Conveniently the antibody fragment and / or derivative thereof is a single-chain antibody fragment, in particular an ScFv.
See also
A single-chain antibody molecule, such as scFv.
In certain embodiments, the antibody is a single-chain antibody.
In this example a single-chain antibody library was produced including unique peptide " barcodes ".
In a preferred embodiment, the binding moiety is a single-chain antibody.
Single-chain antibody fragments of monoclonal antibodies may be constructed, using standard procedures e . g.
In other embodiments, the antibody can be a single-chain antibody.
Functional equivalents also include single-chain antibody fragments, also known as single-chain antibodies ( scFvs ).
In one embodiment, the binding moiety is a single-chain antibody.
SCFv, single-chain antibody variable region Definitions.
The method of claim 1, wherein the antibody is a single-chain antibody.
An " immunogen " is a single-chain antibody ( scAb ) directed to a viral structural protein.
Conveniently, the antibody may be a single-chain polypeptide, such as a single-chain antibody.
The antibody of the invention may be a single-chain antibody ( also referred to as scFv ).
Optionally, the antibody is a monoclonal antibody, humanized antibody, antibody fragment or single-chain antibody.
Preferably, said heterologous protein is a single-chain antibody variable fragment ( scFv ).
In one embodiment, the antibody molecule introduced by gene therapy is a fully human, single-chain antibody.
The antibody disclosed herein may be a single-chain antibody ( also referred to as scFv ).
Conveniently, the specific binding member may be a single-chain polypeptide, such as a single-chain antibody.
The method is exemplified using single-chain antibody constructs as antibody-ribosome-mRNA complexes ( ARMs ).
A multifunctional cytokine-andbody fusión protein according to claim 10, wherein said antibody is a single-chain antibody.
The binding molecule of claim 26, wherein sc-TCR and single-chain antibody regions have been humanized.
The nucleic acid library of claim 48, wherein the members of said library encode a single-chain antibody.
The composition of claim 15, wherein the single-chain antibody is a single-chain Fv antibody.
Single-chain Antibodies In yet another embodiment, one gene may comprise a single-chain antibody.
Alternatively, another method could involve screening bacteriophage libraries of single-chain antibody fragments ( scFv ) Vicugna.
The polypeptide of any one of claims 1 to 11 that is a bispecific single-chain antibody.
Preferably the antibody is a single-chain polypeptide, e.g. a single-chain antibody molecule, such as scFv.
In contrast, a mono-valent library displays, on average, one single-chain antibody per viral particle.
Preferably the binding member is a single-chain polypeptide, e.g. a single-chain antibody molecule, such as scFv.
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Examples of using Single-chain
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A single-chain meganuclease has multiple advantages
Such an antibody can be in a single-chain or heteromultimeric format
Single-chain antibodies can also be prepared
Examples of using Antibody
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Antibody status should be monitored and reported
The kinetics of antibody decline are also similar
Antibody persistence after booster immunisation adults
