Examples of 'soluble polypeptide' in a sentence
Meaning of "soluble polypeptide"
soluble polypeptide: A chain of amino acids that is capable of being dissolved in a solvent, often found in proteins and other biological molecules
How to use "soluble polypeptide" in a sentence
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soluble polypeptide
The soluble polypeptide may be formulated with a pharmaceutically acceptable carrier.
A DNA fragment encoding a desired soluble polypeptide may be subcloned into an expression vector.
In one embodiment, the therapeutic polypeptide is a soluble polypeptide.
The soluble polypeptide may include one or more modified amino acids.
A chimeric or fusión construct comprising a soluble polypeptide of claim 1.
Treating the resulting soluble polypeptide so as to form a biologically active polypeptide ;.
Filtering ; and removing the fluorinated alcohol to recover solid, soluble polypeptide.
Clones with high expression soluble polypeptide were selected for large scale culture.
However, the mannitol formulations yielded less than 60 % recovery of total soluble polypeptide.
In one embodiment, the soluble polypeptide comprises a cellular secretion sequence.
One polypeptide therapeutic agent of the invention is a soluble polypeptide of Ephrin B2 or EphB4.
In a further embodiment, a soluble polypeptide of the present invention is fused to a cytotoxic agent.
Thus, the extracellular region alone, without the transmembrane segment, will often be a soluble polypeptide.
However, there are instances in which a soluble polypeptide can be stimulatory.
Preferably, the soluble polypeptide consists of the extracellular domain or a fragment thereof.
See also
The MILA fragment according to claim 13, wherein said fragment is a soluble polypeptide.
The EphB4 soluble polypeptide of the invention may comprise a globular domain of an EphB4 protein.
In particular embodiments, the composition comprises a soluble polypeptide or an oligomer comprising soluble ULBP polypeptides.
A soluble polypeptide may, for example, lack a transmembrane domain.
In particular embodiments, the composition comprises a soluble polypeptide or an oligomer comprising soluble Pellino polypeptides.
The soluble polypeptide of claim 16, which is an Ig fusión polypeptide.
Preferably, the Fc fusión comprises a soluble polypeptide of the invention, i.e. a Fc, soluble receptor.
A soluble polypeptide comprising the extracellular domain of a GL50 molecule comprising SEQ ID NO, 4.
In certain embodiments, the soluble polypeptide of the invention, may further comprise post-translational modifications.
A soluble polypeptide according to claim 44.
The M-CSF antagonist may be a soluble polypeptide comprising an M-CSF mutein or derivative thereof.
The effective soluble polypeptide according to the present invention may also be a dimer, trimer etc.
An amount of soluble polypeptide in solution can be quantified by ion exclusion ( IEC ) - HPLC.
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