Examples of 'sphingomyelinase' in a sentence
Meaning of "sphingomyelinase"
Sphingomyelinase is an enzyme that catalyzes the breakdown of sphingomyelin, a type of lipid found in cell membranes
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- Any of several enzymes that catalyzes the cleavage of phosphodiester bonds in sphingomyelin
How to use "sphingomyelinase" in a sentence
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sphingomyelinase
Hydrolysis of sphingomyelin is catalyzed by the enzyme sphingomyelinase.
Role of secretory sphingomyelinase in high density lipoprotein remodeling.
Carvedilol also acts as a functional inhibitor of acid sphingomyelinase.
There may be reduced sphingomyelinase activity in some cells.
Heat inactivated chelerythrine had no effect on cell viability nor sphingomyelinase activation.
No acid sphingomyelinase activity was detected.
Treatment with purified recombinant human sphingomyelinase produced similar results.
The use of sphingomyelinase for cosmetic and dermatological purposes is already known.
Radiation alone failed to show increased sphingomyelinase activation over control.
A marked alkaline sphingomyelinase activity has also been observed in the colon and the rectum.
Dose escalation enzyme replacement therapy for treating acid sphingomyelinase deficiency.
Marker for acid sphingomyelinase disorders and uses thereof.
Ceramide production and a coordinate decrease in sphingomyelin mass followed the increase in sphingomyelinase activity.
Another possibility is to use sphingomyelinase to convert sphingomyelin into ceramide.
Clemastine does also act as FIASMA functional inhibitor of acid sphingomyelinase.
See also
The catalytic mechanism of acid sphingomyelinase is the hydrolysis of sphingomyelin to ceramide and phosphorylcholine.
Clofazimine does also act as FIASMA functional inhibitor of acid sphingomyelinase.
This study implicated acidic sphingomyelinase as a component of the apoptotic response in some tissues.
Benzatropine also acts as a functional inhibitor of acid sphingomyelinase FIASMA.
The mixed micellar assay for sphingomyelinase activity was used to quantitate increased enzymatic activity.
Astemizole does also act as FIASMA functional inhibitor of acid sphingomyelinase.
A highly active neutral sphingomyelinase was observed for the first time in ram spermatozoal plasma membranes.
Biperiden does also act as FIASMA functional inhibitor of acid sphingomyelinase.
Acid sphingomyelinase activity was removed without affecting AC activity.
The amount of probe bound increases with sphingomyelinase and cstamide treatment.
Sphingomyelinase from Streptomyces species and all other redrugs were obtained from Sigma.
Graph of in-vitro neutral and acidic sphingomyelinase activity normalized to percent of control.
Compound or composition according to claim 9 for use in inhibiting diacylglycerol, acyltransferase or sphingomyelinase.
Figure 1 shows the activity levels of sphingomyelinase in sonicated lactic acid bacteria.
Sphingomyelinase was also capable of reducing the level of the precursor form of SREBP-1.
The method of claim 1 wherein the acid sphingomyelinase is a human acid sphingomyelinase.
Two forms of sphingomyelinase have been implicated in the generation of ceramide following x-rays.
NPA is a lysosomal storage disorder caused by a deficiency in acid sphingomyelinase ( ASM ) activity.
Composition comprising alkaline sphingomyelinase for use as a dietetic preparation, food supplement or pharmaceutical product.
On the other hand, protein kinase C activation does not correspond to sphingomyelinase activity changes.
Levels of anti-human acid sphingomyelinase specific antibodies in the serum were determined by ELISA.
In the classic infantile type A variant, a missense mutation causes complete deficiency of sphingomyelinase.
The method of claim 1 wherein the acid sphingomyelinase is administered vía an indwelling catheter.
Sphingomyelinase induced a dramatic change in the relative amounts of precursor and mature SREBP-1.
Methods of removing contaminating acid sphingomyelinase activity ( ASM ) from the rAC preparations were developed.
This induction was consistent with the kinetics of TNF-a mediated activation of neutral sphingomyelinase ( N-SMase ).
The acid sphingomyelinase enzyme ( ASM ) that is defective in NPA converts sphingomyelin to ceramide.
Ca2 + and cholesterol were found to inhibit sphingomyelinase activity.
The acid sphingomyelinase enzyme ( aSM ) converts sphingomyelin to ceramide.
One of these enzymes is called acid sphingomyelinase ( ASM ).
Three different types of sphingomyelinase ( SMase ) have so far been identified.
The kinetics of SREBP-1 maturation is consistent with the activation of neutral sphingomyelinase by TNF-a.
Acid Sphingomyelinase is something that is required in order to metabolize a lipid called, ' sphingomelin . '.
Cells were treated with either TNF-a, sphingomyelinase or C2-ceramide at the indicated concentrations.
Figure 2C is a representation of a Western immunoblot showing expression of TNF-a, sphingomyelinase and C2 ceramide.
