Examples of 'thrombin inhibitors' in a sentence
Meaning of "thrombin inhibitors"
Thrombin inhibitors are substances or medications that interfere with the action of thrombin, a key enzyme in the blood coagulation process. They are used in medical treatments to prevent the formation of blood clots and reduce the risk of thrombotic events, such as deep vein thrombosis or stroke
How to use "thrombin inhibitors" in a sentence
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thrombin inhibitors
Discovery and development of direct thrombin inhibitors.
Indirect thrombin inhibitors include heparin and warfarin.
The novel compounds are preferably thrombin inhibitors.
Preferably the thrombin inhibitors are boropeptides.
The salts of the disdosure are thrombin inhibitors.
Many types of thrombin inhibitors are already known in the art.
Compounds of the invention are bicyclic pyridone thrombin inhibitors.
Determination of direct thrombin inhibitors in fluids like serum or urine.
This fact has renewed interest in natural thrombin inhibitors.
The elution of thrombin inhibitors is carried out with benzamidine.
The salts of the disclosure are thrombin inhibitors.
Direct thrombin inhibitors.
New mandelic acid derivatives and their use as thrombin inhibitors.
Examples of well known thrombin inhibitors are heparin and hirudin.
Thrombin inhibitors prevent thrombus formation at sites of vascular injury in vivo.
See also
The invention relates to thrombin inhibitors and substrates.
Direct thrombin inhibitors are medications that interfere with the clotting process.
This invention relates to thrombin inhibitors and substrates.
Direct thrombin inhibitors do not need cofactors in the blood to become active.
Production of thrombin inhibitors.
Thrombin inhibitors can especially be tested according to the method of the invention.
Specific thrombin inhibitors.
Thrombin inhibitors described in prior publications contain sidechains of arginine and lysine.
There is therefore a concrete benefit in using the compounds of this invention as thrombin inhibitors.
This invention relates to thrombin inhibitors which are useful anticoagulants in mammals.
Dabigatran etexilate mesylate is an anticoagulant drug from the class of the direct thrombin inhibitors.
Low molecular weight thrombin inhibitors appear to be of growing importance in this área.
The ECT can provide a direct measure of the activity of direct thrombin inhibitors.
The effective levels of thrombin inhibitors are in the same molar range as heparin.
Biological Results The compounds of the present invention are thrombin inhibitors.
The thrombin inhibitors are also contemplated for the treatment of ischemic disorders.
These medications work as direct thrombin inhibitors or as direct factor Xa inhibitors.
Thrombin inhibitors therefore constitute an effective means of preventing or combating this type of thrombosis.
TECHNICAL FIELD The present invention relates to thrombin inhibitors that are useful as anticoagulants.
The thrombin inhibitors may also be combined with soluble polymers as targetable drug carriers.
Use of the Products of the Disclosure The salts of the disclosure are thrombin inhibitors.
This invention relates to thrombin inhibitors which are useful anticoagulants in humans and animals.
Such compounds may also be described as slow-binding thrombin inhibitors.
The thrombin inhibitors may also be coupled with soluble polymers as targetable drug carriers.
Dabigatran and its acyl glucuronides are competitive, direct thrombin inhibitors.
Synthetic thrombin inhibitors based on the hirudin sequence offer an advantage over native hirudin.
Hence, this assay can detect the presence of direct thrombin inhibitors.
Direct thrombin inhibitors inhibit exogenous thrombin also without the presence of antithrombin or endogenous thrombin.
The 2 classes of NOACs are direct thrombin inhibitors and direct factor Xa inhibitors.
Thrombin inhibitors are a newer type of blood-thinning medicine.
Recently, low molecular weight thrombin inhibitors appear to be of growing importance in this área.
Thrombin inhibitors based on peptidyl derivatives, also having cyclic aminoalkyl guanidines e . g.
In addition, QSAR-studies on thrombin inhibitors were performed by Jorgensen et al.
The thrombin inhibitors provided by this invention are represented by the following formula 1 . wherein.
How do direct thrombin inhibitors work?
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