Examples of 'thrombin receptor' in a sentence
Meaning of "thrombin receptor"
thrombin receptor - This refers to a protein molecule in the body that is capable of binding to the enzyme thrombin. Thrombin receptors play a crucial role in blood clotting and are often targeted in medical research for conditions related to coagulation disorders
How to use "thrombin receptor" in a sentence
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thrombin receptor
Active metabolite of a thrombin receptor antagonist.
One thrombin receptor antagonist is a compound of the formula,.
Crystalline polymorph of a bisulfate salt of a thrombin receptor antagonist.
Other substances, including thrombin receptor agonists and batroxobin, can also be used to activate fibrinogen.
Methods of measuring inhibition of platelet aggregation by thrombin receptor antagonists.
Thrombin receptor antagonists are also known as protease activated receptor ( PAR ) antagonists.
The compounds produced thereby are useful as thrombin receptor antagonists.
NPAR is a high-affinity thrombin receptor present on the surface of most cells.
Process for the production of a crystalline polymorph of a bisulfate salt of a thrombin receptor antagonist.
Figure 4A illustrates the thrombin receptor with its seven transmembrane domains.
The medicament comprises agonists of the non-proteolytic thrombin receptor.
The compounds of the present invention are thrombin receptor antagonists, particularly PAR-1 antagonists.
One thrombin receptor antagonist is compound A, and salts thereof,.
The methods described can be used to produce other thrombin receptor activity peptides.
In addition, vorapaxar inhibits thrombin receptor agonist peptide ( TRAP ) - induced platelet aggregation without affecting coagulation parameters.
See also
A general process is also disclosed therein for preparing such thrombin receptor antagonist compounds.
Other platelet-activators can be used in place of the thrombin receptor activating peptides described above.
In a further embodiment the kit additionally comprises a platelet activator, such as a thrombin receptor activating peptide.
GPIb also serves as a thrombin receptor.
The structure of V31 is very similar to the thrombin receptor.
Immediate-release tablet formulations of a thrombin receptor antagonist.
A synthetic 14 amino acid polypeptide which corresponds to the internal thrombin receptor ligand was radiolabeled.
The kit of Claim 15 which further comprises a thrombin receptor activating peptide.
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Examples of using Thrombin
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Thrombin is central to the process of blood clotting
During the incubation prothrombin is converted to thrombin
Once thrombin is activated it converts fibrinogen to fibrin
Examples of using Receptor
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Receptor is not sensitive to the type of change
Is that why that receptor network existed
This receptor can exist in three conformations
