Examples of 'tnfα' in a sentence
Meaning of "tnfα"
tnfα (noun) - tumor necrosis factor alpha, a cell signaling protein involved in inflammation and immune system responses
How to use "tnfα" in a sentence
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tnfα
Human antibodies that bind human TNFα.
Reductions in serum TNFα were also observed.
Cimzia binds to a specific protein called tumour necrosis factor α TNFα.
The replacement TNFα acts in same way as the naturally produced protein.
Approximately half of patients had previously failed TNFα antagonist therapy.
In particular TNFα and IFNγ drive the formation and maturation of phagosomes.
This was achieved using nanoplates functionalised with antibodies against TNFα.
Infliximab inhibits the functional activity of TNFα in a wide variety of in vitro bioassays.
NK cells work to control viral infections by secreting IFNγ and TNFα.
Experimental data show that TNFα is essential for the clearing of intracellular infections.
Patients with innate immune suppression produce reduced amounts of TNFα when their blood is stimulated.
TNFα is a member of a group of other cytokines that all stimulate the acute phase reaction.
Infliximab does not cross react with TNFα from species other than human and chimpanzees.
Species cross-reactivity of infliximab is limited to human and chimpanzee TNFα.
Medicines that bind to TNFα are also called TNF blockers.
See also
A TNFα receptor-blocking fusion protein, etanercept has showed encouraging results.
Approximately one-third of patients had failed prior TNFα antagonist therapy.
Effect of TNFα antibodies in CED.
In this pathology, inflammation is mainly dependent on the pro-inflammatory cytokine TNFα.
In one aspect, the TNFα is human TNFα and the subject is a human subject.
Both antagonists also enhanced the mRNA levels of IL-1β without affecting those of TNFα.
TNFα is a key pro-inflammatory cytokine with a central role in inflammatory processes.
Cimzia was shown to neutralise membrane associated and soluble human TNFα in a dose-dependent manner.
Discovery sheds light on TNFα protein 's role in impairing memory in Alzheimer 's disease.
Flixabi works by blocking the action of a protein called ‘ tumour necrosis factor alpha ' TNFα.
However, there are only a few studies testing TNFα therapeutics in Alzheimer 's conditions.
Inflectra works by blocking the action of a protein called ‘ tumour necrosis factor alpha ' TNFα.
A TNFα antagonist and / or vedolizumab.
In GEMINI II, approximately half of patients had previously failed TNFα antagonist therapy.
The secreted form of human TNFα takes on a triangular pyramid shape, and weighs around 17-kDa.
Ginger helps to suppress inflammation-related substances like TNFα and COX-2.
Cimzia has a high affinity for human TNFα and binds with a dissociation constant ( KD ) of 90 pM.
In resting subjects, endotoxin induced a 2 - to 3-fold increase in circulating levels of TNFα.
Further, children who died from influenza had markedly lower TNFα production capacity compared with survivors . ”.
I blocked TNFα function with XPro1595, a selective inhibitor of soluble TNFα.
They are still investigating why TNFα induces A20 in this scenario.
Both TNFα and IL-13 have a direct effect on increasing intestinal lining leakage ² ⁰.
Including corticosteroids, immunomodulators, and/or TNFα antagonists (including primary non-responders).
TNFα and IL-10 act as proinflammatory and immunosuppressors, respectively.
Tasonermin is a tumor necrosis factor alfa-1a ; TNFα -1a, produced by recombinant DNA technology in E. coli.
A sandwich ELISA was used for the detection and assay of IL-1β, IL6 and TNFα.
