Examples of 'tnf-α' in a sentence
Meaning of "tnf-α"
tnf-α (noun) - Short for Tumor Necrosis Factor-alpha, a protein involved in systemic inflammation and various immune responses within the body. It is a cytokine playing a key role in regulating immune cells and pathways
How to use "tnf-α" in a sentence
Basic
Advanced
tnf-α
Adipocytes generate TNF-α and other interleukins.
We focused more specifically our study on TNF-α.
Current results about the molecules controlling TNF-α expression are also presented.
Inflammation is a very prominent response to TNF-α.
Tnf-α plays a pivotal role in inflammatory diseases such as arthritis, colites and psoriasis.
The electroactivation of these cells would be followed by the release of TNF-α.
Effect of a fermented nutraceutical on thioredoxin level and tnf-α signalling in cirrhotic patients.
Microglia-produced TNF-α causes neural tissue to undergo apoptosis and increases inflammation.
Some studies suggesting that glucantime ¿ enhances phagocytosis and tnf-α production by phagocytes.
The other TNF-α gene polymorphisms had little or no association with autoimmune diseases.
This protein is potentially involved in resistance of cells to the apoptosis-inducing affect of TNF-α.
The hyper-activated macrophages secrete TNF-α which recruits multiple monocytes to the site of infection.
TNF-α may activate both proapoptotic and antiapoptotic pathways.
It is a monoclonal antibody that blocks the biological action of TNF-α tumor necrosis factor-alpha.
The amount of TNF-α in the medium was measured by ELISA.
See also
Administration of Bifidobacterium breve decreases the production of TNF-α in children with celiac disease.
TNF-α is often involved in different signaling pathways to regulate apoptosis in the cells.
However a review of the literature has suggested that TNF-α inhibitors may be superior then anakinra.
Thereafter, TNF-α protein was measured by ELISA in the supernatant of the cell culture.
Macrophages that ingest the MAP bacterium are associated with high production of TNF-α.
So, reduction of TNF-α and other inflammatory factors can improve the treatment of NAFLD.
Also found on human chromosome 6 is the cytokine TNF-α which is also associated with RHD.
TNF-α then triggers apoptotic pathways through the activation of caspases, resulting in cell death.
Mast cells and macrophages are also involved, secreting TNF-α along with the T cells.
TNF-α is produced by activated macrophages.
ALEC strains replicate extensively inside macrophages inducing the secretion of very large amounts of TNF-α.
Excess TNF-α has been shown to be lethal.
Specifically, sulfatide is capable of inhibiting TNF-α secretion.
Inhibition of TNF-α in an animal model.
The monoclonal antibody infliximab is a mouse-human chimeric antibody to TNF-α.
Other monoclonal antibodies targeting TNF-α are golimumab, adalimumab, and certolizumab pegol.
It works by binding to TNF-α.
Both capture soluble TNF-α in the plasma ; etanercept also captures TNF-β.
This effect was accompanied by decreases in il1-β and tnf-α levels in the peritoneal fluid.
Since TNF-α plays such an essential role, it is an ideal target for anti-inflammatory substances.
Simponi works by blocking the action of a protein called ‘ tumour necrosis factor alpha ' TNF-α.
TNF-α is a chemical messenger ( cytokine ) and a key part of the autoimmune reaction.
It has also led to increased secretion of TNF-α and IL1.
TNF-α neutralization inhibition of TNF-induced apoptosis.
The salivary levels of TNF-α and IL-6 were measured using ELISA test.
TNF-α neutralization reporter gene assay.
The T cells produce an excess of cytokines, including TNF-α and interferon-gamma IFNγ.
The dosages of serum tnf-α and il-10 were performed by enzyme linked immunosorb.
Recombinant Human TNF-α.
Once released, TNF-α will “ recruit ” other defence cells in the organism.
An inflammatory state was induced by pro-inflammatory cytokines TNF-α and IL-1β.
From, ROS-mediated TNF-α and MIP-2 gene expression in alveolar macrophages exposed to pine dust.
Participants with a better adherence to the HEI-2015 score had lower levels of circulating TNF-α.
PuA upregulated colonic PPAR-δ activation and suppressed TNF-α and MCP-1 expressions.
