Examples of 'unfolded protein' in a sentence
Meaning of "unfolded protein"
unfolded protein: An 'unfolded protein' is a molecular structure of a protein that has not achieved its correctly folded, functional conformation. In biological contexts, such as genetics, biochemistry, or cell biology, unfolded proteins are often associated with misfolding, aggregation, or cellular stress, which can lead to dysfunction, disease, or abnormal physiological conditions
How to use "unfolded protein" in a sentence
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unfolded protein
Through regulation of the unfolded protein response.
Unfolded protein response contributes to sudden death in heart failure.
Mitochondrial unfolded protein response.
An unfolded protein may be threaded through a nanopore of the present disclosure.
A new type of biological clock regulates the unfolded protein response.
The accumulation of unfolded proteins initiates the activation of the unfolded protein response upr.
The apical section contains a large number of hydrophobic binding sites for unfolded protein substrates.
A computational method for rapid prediction of unfolded protein residual dipolar couplings was also developed.
ER unfolded protein response.
Experimenters rapidly trigger the folding of a sample of unfolded protein and observe the resulting dynamics.
Consequently, they shift the chemical equilibrium of the unfolding reaction towards unfolded protein.
This reaction is known as the unfolded protein response, the researchers explained.
These data were used to calculate the apparent fraction of unfolded protein ( Fapp ).
For proteins that unfold irreversibly, unfolded protein often forms insoluble aggregates.
The unfolded protein response ( UPR ) is a cellular stress response related to the endoplasmic reticulum.
See also
ROS production disrupts protein folding and induces the unfolded protein response UPR.
The unfolded protein response ( UPR ) is then activated by the translated Haclp.
We focused in particular on the endoplasmic reticulum unfolded protein response ( UPRER ).
NR also stimulated mitochondrial unfolded protein response, which protects against mitochondrial disease ( R ).
The protein Orm2p is required for resistance to agents that induce the unfolded protein response.
Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha.
Expression of chaperones is regulated by a number of mechanisms, including the unfolded protein response ( UPR ).
Components of the unfolded protein response ( UPR ).
Furthermore, this cellular lipointoxication can appear by the induction of the unfolded protein response ( UPR ).
First, the “ mitochondrial unfolded protein response ” ( UPRmt ), which protects mitochondria from stress stimuli.
In response to these changes, an adaptive mechanism is activated, UPR ( for Unfolded Protein Response ).
When an unfolded protein ( UFP ) is produced, however, BiP binds to such UFP.
ER stress and the subsequent unfolded protein response ( UPR ).
HSP90 has been implicated in activation of the unfolded protein response ( UPR, ).
FIG . 5, OAG and LPA reduce the unfolded protein response ( UPR ) in lipointoxicated yeasts.
XBP1 is part of the endoplasmic reticulum ( ER ) stress response, the unfolded protein response ( UPR ).
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